Correlation Analysis Related To Coronary Heart Disease And Abnormal Glucose Metabolism In Patients With Lipoprotein (a) And Coronary Lesions

Objective: To study coronary heart disease and sugar metabolism in patients with abnormallipoprotein (a) with coronary artery disease.Methods: Coronary angiography was Performed for 470 Patients during May 2010 to December2011 in the hospital of Cardiology and confirmed with coronary heart disease patients, and askedin detail about the sex, age, history of hypertension, history of diabetes, smoking history. Fastingplasma glucose (FPG) and 2h postprandial plasma glucose (2hPG), total cholesterol (TC),triglycerides (TG), high-density lipoprotein cholesterol (HDL-C)low-density lipoproteincholesterol (LDL-C), lipoprotein (a) [Lp (a)] level was measured in the next day early morning .The results of coronary angiography was determined by two experienced physicians in theDepartment of Cardiology. All patients was divided into one，two，three lesions group bystenosis (≥50%) involving the left main、left anterior descending artery、circumflex artery orright coronary artery and they make quantitative analysis of coronary artery stenosis. Allpatients in accordance with the fasting glucose levels were divided into four groups. Coronaryheart disease risk factors, and lipoprotein (a) and coronary lesions was compared betweengroups using SPSS11.5 statistical software package for statistical analysis , measurement datademonstrated by x±s,progressing t-test ,seting up P<0.05,the difference is distinguished, andcount data deploying chi-squar check-up.RESULTS: With the gradual increase of the fasting blood glucose concentrations, Lp (a)single-vessel disease, three lesions involving the circumflex artery incidence gradually increased,compared with the NGT group . The difference was statistically significant (P <0.05). Theremaining three groups compared with the NGT group ,which Lp (a) and the degree ofcorrelation of coronary lesions were higher than the NGT group.Conclusion: Involving the coronary and LP (a) were higher than NGT group in patients with thecoronary heart disease and abnormal glucose metabolism; the degree of correlation of coronaryheart disease and abnormal glucose metabolism in patients with LP (a) and coronary lesions werehigher than NGT group.