| To explore the relationship of different LV geometry and diastolicfunction of LV using quantitative tissue velocity imaging among hypertensionpatients. With42cases of healthy volunteers and107hypertension patientsstudied, observe motion characteristics of LV at tissue velocity curve. Withelectrocardiogram connected,we record the conventional2-chamber views ofcardiac apex long axis view near sternum and apical4-chamber,observemotion of every Atrioventricular cavity and Chamber wall, conventionallyrecord parameters of LAD, LVDed with two-dimensional and flow spectrumDoppler echocardiogram (LVDed、IVSth、E/A，etc).According to the Ganau’s classification hypertensive patients werecounted LVMI and RWT then were classified into four groups: normalgeometry (I):12cases had normal LVMI and RWT; concentric remodeling(II):37cases had higher RWT and normal LVMI; concentric hypertrophy(III):43cases had both larger LVMI and RWT; eccentric hypertrophy (IV):12cases had higher LVMI and normal RWT.With the software of QTVI to obtain the synchronous myocardial tissuedoppler curve of the6sides (Bis、Mid and Ap,etc) through apical4-chamberview(posterior septum, lateral),the apical2-chamber view(inferior, anterior)and cardiac apex long axis view(anterior septum, posterior).With statistical software SPSS16.5, every parameter was analyzed bysingle factor analysis of variance(ANOVA),using “mean+-standard deviation”to express and the way of LSD to comparative test,that P<0.05is meaningfulin statistics. Results showed that:1.The parameters of two-dimensional and flowspectrum Doppler echocardiogram: LAD in every EH group were larger thangroup I（P﹤0.05）, and the numerical value of group I was closed to groupconcentric restructure(II),the numerical value of the group of centrifugalhypertrophy (IV) enlarged apparent particularly than the three groupsbefore,otherwise, in which group III and IV was different particularly withother groups(P<0.05). The difference between blood flow filling maximumE、A、E/A and mitral ring Va was no meaningful in statistics(P>0.05). Themaximum velocity of blood flow rapid filling maximum velocity spectrum (E)was different and below group I in group II and III (P﹤0.05); Atrialcontraction maximum velocity (A) in group II and III was higher than group I(P﹤0.05);in group II and III, E/A<1,which reduced obviously with group I,otherwise, in group I and IV,E/A>1.2.The indexes of QTVI:The tissue Dopplerimaging of basal level had this phenomenon: Ve in every hypertension groupexcluded group I in anterior basal segment, were lower than group （IP﹤0.05）,dissociative wall higher than ventricular septum. Va in posterior septum ofgroup I and interior of group II were higher than control group.Va in group IVlower than in groups I and II, especially in ventricular septum and lateral wall.Ve/Va in dissociative walls had no distinguish among groups. Ve/Va＜1appeared in posterior septum、interior and posterior wall of hypertension groupsII and III, distinctly compared with group I（P﹤0.05）. Group I had Ve/Va＞1and group IV had Ve/Va＞2. Analysed every parameter synthetically, theLV diastolic function decreased in hypertension patients despite of ventriculargeometry. After comprehensive analysis, diastolic function of LV in everyhypertension group reduced to varying degrees.QTVI could evaluate the impaired degree of diastolic function of LV moreearlier and sensitive than routine echocardiography for hypertension patients, while, it could help judge Pseudo normalization of diastolic function of LV, andhad higher sensitivity for estimating the impaired degree.With different LVconfiguration,it would find the change characteristics of diastolic function ofLV because of hypertension, on the other hand,it would improving theaccuracy of evaluating the diastolic function of LV,and had importantsignificance for the diagnosis、treatment and prognosis of hypertension inclinical. |
PDF Full Text Request