| Objective: Arteriosclerosis increased arterial stiffness, which easily cause diastolic dysfunction.Brachial-ankle pulse wave velocity (baPWV) is a classic indicator of arteriosclerosis and can be used as anindicator of cardiac function. Today, relationship baPWV and left ventricular diastolic function has not yetapparent. By means of researching them, this study investigate whether baPWV is an early index toevaluate left ventricular dysfunction, while it could provide clues for more earlier for detecting andintervening left ventricular diastolic dysfunction.Methods:100of essential hypertensive patients were enrolled and extracted peripheral venous blood todetect related biochemical index. Tissue Doppler Imaging （TDI） echocardiography, through themeasurement of relevant parameters (E、A、e’ and a’), is used to evaluate left ventricular diastolic function.According to E/e ’, patients will be divided two groups: the left ventricular diastolic dysfunction group andthe normal group, and baPWV is used to assess atherosclerosis.Results:1. baPWV were significantly higher in the left ventricular diastolic dysfunction group compared tothe control group (P <0.05).2. A linear correlation analysis proved that baPWV were positively correlated with E/e’(r=0.388, P=0.000),baPWV were negative associated with left ventricular diastolic function in essential hypertension, that isthe higher the baPWV increased, the worse would be left ventricular diastolic function.3. baPWV were positively associated with age, HR, SBP, PP, FBG, IVS, LVD and LVPW(P <0.05); Age,FBG, HR and PP significantly influenced baPWV.4. Age, baPWV, LVD and LVPW were significant factors that influenced left ventricular diastolic function.Conclusion: Atherosclerosis was a primary mechanism to prompt left ventricular diastolic dysfunction;baPWV can be used as an indicator assessment of left ventricular diastolic function. |
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