Clinical Analysis Of Cellular Leiomyoma And Uterine Leiomyosarcoma

Objective: To investigate the clinicopathological features and postop-erativerecurrence of Cellular leiomyoma and uterine leiomyosarcoma to help earlydiagnosis and clinical treatment of choice.Materials and Methods:Random sample of Kyrgyzstan sophomore January2007to December2011, the pathological return to the Cellular leiomyoma,159cases and thesepatients were admitted in this period guitar sophomore or guitar freshmanHospital11cases of postoperative pathological uterine leiomyosarcoma clinicaland pathological data were retrospectively analyzed.Results:1、2007-2011calendar year CUL proportion of total annual UL patientswas9.7%,8.97%,6.41%,11.00%,6.71%.2、The average age of onset: CUL non-recurrent group was43.22±6.76years. CUL recurrence group was38.29±9.50years, LMS group was54.91±8.25years old, the age of onset of LMS patients was significantly higher thanthe former two (P <0.05).3、The average maternal: CUL non-recurrent group was2.36±1.24, the recurrent group was2.00±1.30times, there was no significant difference (P>0.05). LMS group was3.55±1.21times higher than the two groups CULpatients, the difference was statistically significant (P <0.05). Each group ofpatients age41years and above average production, CUL non-recurrent groupwas2.54±1.27times, the the CUL recurrence group was2.17±1.27times,the LMS group,3.55±1.21times LMS group is still higher than before both (P<0.05).4、 CUL patients with diverse clinical manifestations, no significantdifference between the non-recurrence group and recurrence group of patientswith clinical manifestations are menstrual change is the most common clinicalmanifestations,43.45%of the non-recurrent group and50%of patients withrecurrent group performance to shorten the menstrual cycle,menstruation,increased by the amount of clinical symptoms. Approximately27.83%CULrecurrence-free group patients and42.86%recurrence in patients without anyclinical symptoms, physical examination only. Irregular vaginal bleeding(45.45%), uterine leiomyosarcoma patients with clinical manifestations ofamenorrhea after the main performance, but also suffer from abdominal pain(27.27%), abdominal mass (27.27%) and other symptoms.5、Two groups of the CUL patients of the uterus and the median of thelargest myoma diameter of7cm,5.5cm, no significant difference (P>0.05).LMS for8.5,9cm. When the uterine diameter>13cm, or the largest myomadiameter>10cm, the composition of the LMS patients was significantly higherthan CUL non-recurrent group (P <0.05).6、All the CUL patients once surgery OK fibroids nuclear in addition tosurgery by73cases,11cases of recurrence, the recurrence rate was15.1%;hysteroscopic myomectomy by16cases,2cases of recurrence, the recurrencerate was12.5%;22cases a hysterectomy surgery,1case of recurrence, therecurrence rate was4.5%; hysterectomy resection in48cases without recurrence. OK fibroids Nuclear the CUL patients in addition to surgery andhysteroscopic myomectomy, the recurrence rate was significantly better thanhysterectomy resection, the difference was statistically significant (P <0.05).7、LMS group patients, two cases because of uterine fibroids hysterectomysurgery. Three cases of recurrence, three years, five cases of deaths, theproportion of patients accounted for62.5%of all LMS group of patients with11patients.Conclusion:1、The CUL patients with the incidence in recent years, no significantincrease or reduce;2、CUL occur in women aged30-50, the LMS occurred in postmenopausalelderly women;3、The average yield of the LMS in patients higher than CUL;4、CUL patients with diverse clinical manifestations, which is the mostcommon menstrual changes. LMS patients with amenorrhea, irregular vaginalbleeding is the main clinical manifestations. Both clinical symptoms are nottypical;5、Uterine diameter>13cm, or the maximum myoma diameter>10cmwhen you consider the possibility of suffering from LMS;6、The CUL patients with fibroids nuclear in addition to surgery andhysteroscopic myoma resection by postoperative recurrence. HysterectomyCUL more thorough and effective; 7、The LMS patients were treated by operation, the surgical approach andmore for the whole uterus resection+double-oophorectomy, postoperativeadjuvant chemotherapy, but the results are poor. Postoperative recurrence andpoor prognosis.