The Impact Of Tongfuxingshen Capsule Of Parkinson’s Disease Patients With Functional Constipation And Preliminary Study Of Its Efficacy

ObjectiveParkinson’s Disease(PD), also named as parelysis agitans, is a kind of neurodegenerative disease, which usually occurs in middle-aged or senile patients. At present, there is no medicine or surgical which is effective enough to stop the development of this disease. In addition to motor symptoms, in recent years also noted, almost all patients with PD will appear different types and degrees of non-motor symptoms, on the life quality of patients with PD influence really. In the early days of PD patients with tremor, akinesia, later period is often accompanied by salivation, constipation, autonomic dysfunction, which is PD constipation in patients with the most common manifestations of autonomic dysfunction. A large number of clinical and experimental has been demonstrated, tongfuxingshen capsule can improve symptoms of constipation, improve patients’living treatment, but the present tongfuxingshen capsule in the treatment of Parkinson’s disease with functional constipation according to deficiency of objectivity. Clinical studies can be better in PD patients with constipation clinical observation.MethodsChosing60cases of Parkinson’s disease. In traditional Chinese medicine and Western medicine based on routine treatment, The use of the tongfuxingshen Capsule on Parkinson’s disease patients with functional constipation were treated, and with the use of Maren soft capsule treatment compared to the control group, to observe the tongfuxingshen capsule in the treatment of functional constipation in the clinical curative effect, of Parkinson. Recorded before treatment and after treatment of scale, counting and timing results, using the t test (with normal distribution measurement data) and The chi-square test method on its efficacy results were analyzed statistically, with groups of paired T test analysis on its treatment effect.ResultsThe treatment group before treatment, second weeks of treatment symptom integral T test, obtains the P<0.05, prompt treatment group two time there were statistically significant differences.On two groups of patients before treatment, second weeks of treatment of defecation with degree of difficulty and stool degree of soft and hard respectively were analyzed by T test, two groups before treatment integral P>0.05, prompting the differences were not statistically significant; while the two group treated with second weeks of defecation interval integral P<0.05, prompting the difference was statistically significant.Compared with the control group, The Treatment group efficacy without significant difference.(P>0.05)ConclusionThe Tongfuxingshen Capsule can improve Parkinson’s patients with functional constipation. Its curative effect is exact. But Compared with the control group, Its efficacy without significant difference.(p>0.05).To some extent, improve the quality of life of Parkinson’s patients with functional constipation.