Investigate Of131I Therapy In Postoperative Patients With Differentiated Thyroid Carcinoma

1Objective:To observe the therapeutic and main influential factors2Methods:(1).Research: collect the data of Department of nuclear Medical of first Affiliated hospital of shan xi medical university And retrospective analyze44postoperative patients with differentiated thyroid carcinoma,observe the therapeutic and investigate the main influential factors(2) Experimental program:1collected from March2010to March2012, First Affiliated Hospital of Shanxi Medical University Department of Nuclear Medicine, thyroid cancer, medical records confirmed that the general condition of patients for differentiated thyroid cancer, non-pregnancy (all cases were confirmed by surgery and postoperative cases, WBC>3.0×109/L)2Dose:(1) Clear thyroid treatment:120mci.(2) Metastases treatment:150-200mci3The judgment of the treatment effect::(1) Clear thyroid treatment:When disabled thyroid tablets4-6weeks TSH levels higher than normal, thyroid iodine uptake rate of less than1%of1311-WBS imaging the thyroid bed and thyroid tissue imaging that clear A completely, otherwise clear the incomplete.(2) Metastases treatment:The cure:1311whole body phenomenon negative, in HTG\u003c1.0μg/L, serum TGAb. Invalid:the transfer of the stove iodine uptake was no significant change in scope, or the emergence of new metastases.4Statistical methods:Using χ2test All data were analyzed by SPSS1010statistical software.test Standard:α=0.05, P<0.05Has significance.3Resultsamong44postoperative patients with differentiated thyroid carcinoma,31achieve successful thyroid remnant ablation at first dose.13failed,clearance70.45%.50metastases were cured24,improved in17,ineffective9,total efficiency of82%.4Conclusion:(1) Differentiated thyroid cancer after1311to remove residual thyroid tissue is a safe and effective method. Average120mci therapeutic dose get a good clean results. Most patients receive one-time removal Mainly related to the surgical procedure, residual thyroid size patient age, serum of TSH, in HTG and other factors.(2) Significantly better treatment for lymph node metastasis in the treatment of metastases to other distant metastases. Average dose treatment,the former was significantly less than the latter. And cervical lymph node metastasis, which may easily be found that surgical procedures have been implemented in the lymph node dissection, the removal of the majority of lesions related to. Also may be due to the different parts of metastases uptake of1311ability differences...