The Clinical Outcome And Evaluation Of Fetal Tricuspid Regurgitation And The Influence To The Blood Flow Frequency Spectrum Of Umbilical Artery And Middle Cerebral Artery

Objiective1. To evaluate the reason and the clinical value of fetal tricuspid regurgitation.2. To observe and evaluate the change of the blood flow frequency spectrum of umbilicalartery and middle cerebral artery in varying degrees of fetal tricuspid regurgitation.Materials and Methods1. research objectChoose3384singleton pregnancy women who were in routine examinations in prenatalcare in our hospital from August2004to October2011. The pregnancy period from20to36week, the average gestational age was29.1week. Including653high-risk pregnantwomen,2．instruments and methodsThe instrument is Philips7500, GE Voluson730color Doppler ultrasonographyequipment,Screening tricuspid regurgitation cases with fetal echocardiography, Classification thepositive cases on the bases of regurgitation degrees.To evaluate the prognosis of varyingdegrees of tricuspid regurgitationUsing color Doppler ultrasound to measure the blood flow frequency spectrum ofumbilical artery and middle cerebral artery, that is Pulse index(PI), resistance index(RI),and the peak systolic/diastolic ratio of umbilical artery and middle cerebral artery.Toevaluate the change of the blood flow frequency spectrum of umbilical artery and middle cerebral artery in varying degrees of fetal tricuspid regurgitation,to get some related laws.Results1.103cases of fetal tricuspid regurgitation were picked up, the detection rate is3.04%.Among the level I and level II regurgitation cases,the number of the cardiac andextracardial deformities was little,and the deformities often not too serious.The pregnantwomen often have normal childbirths. Among the level III and level IV regurgitationcases,almost all have serious cardiac and extracardial deformities,the number of theinduced labour is high.2. Among the level I and level II regurgitation cases, he blood flow frequency spectrum ofumbilical artery and middle cerebral artery have no obvious difference with the controlgroup’s (P>0.05). With the tricuspid regurgitation levels increased, among the level III andlevel IV regurgitation cases, the PI and RI and S/D number rised，had obvious differenceswith the control group’s (P<0.05). Among the level III and level IV regurgitation cases, thePI and RI and S/D number of Middle Cerebral Artery decreased, had obvious differenceswith the control group’s (P<0.05).Conclusions1. The level I and level II fetal tricuspid regurgitation cases have low specificities, thefetuses most were normal after birth. The level III and higher fetal tricuspid regurgitationcases often combined with obvious abnormal cardic and extracardiac structure. Suggestingthe severity of fetal tricuspid regurgitation has close relations with fetal cardiovasculardeformities and the severity of deformities.2. Among the mild level of fetal tricuspid regurgitation cases, the blood flow frequencyspectrum of umbilical artery and middle cerebral artery have no obvious difference withthe control group’s (P>0.05). Among the moderately severe level of fetal tricuspidregurgitation cases, the PI and RI and S/D number of umbilical artery rised, suggesting thatthe moderately severe level of fetal tricuspid regurgitation influenced the functions ofplacentas, the placentas circulation resistance rised. Directly influence the exchange ofnutrition and oxygen between the fetal circulation and the maternal circulation. Caused varying degrees of intrauterinefeta anoxia. Among the moderately severe level of fetaltricuspid regurgitation cases, the PI and RI and S/D number of middle cerebral artery cutshort, suggesting intrauterinefetalanoxia, first to guarantee the blood supply of brain.