Clinical Research On A Treatment Of Nephrotie Syndrome With Modified Fangji And Astragalus Deeoetion

ObjectiveThis clinical study contrast the astragalus tonga have reduced treatment nephrotic syndrome patients for clinical curative effect; Through the comparison with renal soup, observe the astragalus tonga have reduced treatment nephrotic syndrome patients for clinical curative effect.MethodsThe research object for patients with nephrotic syndrome. Cases are for2011years source February to October in Taiwan are traditional Chinese medicine for Chinese medicine clinic patients with nephrotic syndrome.60patients with accord with standard of adults PNS into patients were randomly assigned to the treatment group and control group.30cases in the kidney to soup treatment, the treatment group of30cases to prevent astragalus tonga have reduced treatment, oral8weeks. Patients with traditional Chinese medicine syndrome integral, bloated subsidise24h urine protein days, quantitative, plasma albumin, blood fat and renal function index for observation, in the end, treatment before treatment respectively in two groups each index patients were evaluated. After the clinical research, clinical material timely summary, into the computer and software is built with Epi Data3.01database, data management, with SPSS software for statistical analysis. In two groups of clinical treatment effect, the total clinical symptoms and signs efficacy analysis and comparison of the statistics, and finally an objective evaluation of clinical curative effect and its safety. Statistical methods:classification material with2inspection, level with two sample data comparison Wilcoxon rank and inspection (correct), two sample mean differences with more t test or Wilcoxon rank and inspection, compared with before and after their matching t test or Wilcoxon matching rank and inspection. Statistics for the calculation SPSS17.0statistical software statistical analysis.ResultsThe study participants were qualified example,30cases in treatment group and control group in30cases). Two groups of spleen and kidney Yang curative effect of TCM syndrome comparison, significant difference, the curative effect of treatment group was better than control. The clinical curative effect of treatment clinical cure rate was23.3%, the significant efficiency is56.6%, the effective rate was13.3%, the total effective rate was93.4%; The control group clinical cure rate was16.6%, the significant efficiency is53.3%, and the effective rate was16.6%, the total effective rate was86.7%. Two groups of comparisons, significant difference. Two groups of clinical total curative effect more, significant difference, the curative effect of treatment group was better than control. The clinical curative effect always clinical cure rate was30%in treatment group and46.6%significant efficiency, the effective rate was16.6%, the total effective rate of93.4%; The control group clinical cure rate was20.0%,43.3%significant efficiency, the effective rate was23.3%, the total effective rate of86.7%. Two groups of comparisons, significant difference. Its total efficient superior to that of the control medicine. In the clinical curative effect of traditional Chinese medicine and syndrome curative effect, the treatment group than controls (P<0.05). Two groups of patients with traditional Chinese medicine treatment of syndrome are better improving function (P<0.05), the improvement of the treatment group was better than control group (P<0.05). The treatment group edema is gone days less than in control group (P<0.05). Two groups of treatment can reduce the24h urine are protein, the treatment group than in control group (P<0.05), the treatment was not observed in adverse reactions.ConclusionModified Fangji And Astragalus Deeoetion in the treatment of adults nephrotic syndrome is superior to that of the control method of medicine. Add to the flavor and astragalus soup have promote edema has faded, improvement of TCM syndrome, reduce the role of the urinary protein. The study was not observed treatment for kidney function and the blood system medicine have obvious damage, clinical application security.