Clinical Research On Hemodynamics Effects Of Patients With Liver Cirrhosis And Portal Hypertension With Liver Stagnation Spleen Weakness And Blood Stasis With Rougan Granule

Objective:Research on effect of Rougan Granule on patients with liver cirrhosis and portal hypertension hemodynamics, evaluation of Rougan Granule in preventing and treating liver cirrhosis portal hypertension and the progress of the dease effectMethods:This experiment selected in accordance with the standards of the patients with cirrhosis and portal hypertension in60cases, in accordance with the principle of randomly divided into the treatment group30examples, the control group of30cases. The two groups were on the basis of routine treatment of Western medicine in the treatment of liver cirrhosis with portal hypertension,the treatment group plus clothing Rougan granule,three times a day, take the medicine after meals; the control group plus propranolol10-20mg,3times a day, To reduce the administration of the former basis of heart rate of20%to25%as the standard.the course of treatment was one month. To observe Rougan granule on the clinical symptoms of liver cirrhosis with portal hypertension before and after treatment.Portal vein inside diameter (DPV) Portal vein flow velocity (VPV), Spleen vein inside diameter (DSV) Spleen vein flow velocity (VSV), and liver function, the effect of TCM and the integral effect, and carries on statistics analysis, draw the conclusionResults:①In two groups after the treatment, the clinical symptoms were improved, the treatment group was superior to control group, comparison between groups was statistically significant (P<0.05).②The liver function index:two groups of patients after treatment of ALT, AST, GGT levels were significantly decreased than before treatment (P<0.05), were compared between groups was statistically significant (P<0.05).③In two groups after the treatment of the portal vein and splenic vein diameter and blood flow velocity is improved significantly (P<0.05), were compared between groups was statistically significant (P<0.05). Conclusion:1Rougan granule can improve the liver cirrhosis and portal hypertension in patients with symptoms and signs.2Rougan granule can reduce the serum levels of ALT, AST, GGT, effectively improve liver function.3Rougan granule can reduce Portal vein and splenic vein, improve blood flow velocity, to reduce portal pressure effect.