The Deifcit Of Decision-making In Patients With Temporal Lobe Cerebral Infarction

Objective: To explore the decision making in patients affected by temporal lobecerebral infarction, based on which tried to provide the new method for detecting thetemporal lobe cerebral infarction.Methods Fifteen patients with temporal lobe cerebral infarction and twenty healthycontrols were examined with the Iowa Gambling Task to assess decision making basedon feedback processing.Results The result showed that temporal lobe cerebral infarction group impaired notonly on the subcomponent of executive task but also decision making on the IowaGambling Task than the HC group. In Iowa Gambling Task, the temporal lobe cerebralinfarction group selected less advantageous cards and less the total amount of gainedmoney than health controls (P<0.05).The study indicated that the health controlsgradually shifted their selections toward the good decks as the game progresses, but thetemporal lobe cerebral infarction group did not exhibit this advantageous shift indecision making. The results also showed that the unilateral lesion side in the temporallobe cerebral infarction had no influence on the performance in Iowa Gambling Task(P<0.05).Conclusions The present study suggests that the decision making impairment inpatients with TLCI, and indicates that temporal lobe might be in involved in decisionmaking processes, and that injures in the left or the right temporal lobe had no influenceon decision making. Impairments of executive functions in patients affected by temporal lobe cerebral infarction, and disadvantageous behavior was associated withexecutive deficits.