| Purposes:Preliminary comparison Nanjing, Macau eczema clinical manifestations, risk factors, similarities and differences of quality of life with TCM Hou, to explore the impact of eczema on quality of life of patients with different geographical and regional Chinese eczema diagnosis and treatment of the law and the accumulation of beneficial for eczema prevention work in the future the information.Methods:Retrospective survey in March2011and March2012in Jiangsu Province Hospital of Traditional Chinese Medicine dermatology, pharmacy outpatient Macau cultivation Church eczema patients to seek treatment for302cases, using the grouping method of the different regions, including Jiangsu Provincial Hospital of Dermatology outpatient Nanjing group, pharmacy outpatient Macau cultivation Church in Macau group. A questionnaire survey on selected cases using statistical observations:(a) general condition and clinical data questionnaire for eczema patients; b. Eczema area and severity index score (EASI score); eczema syndrome differentiation type and dialectical reference standard; e World Health Organization quality of life determination scale a simple table (WHOQOL-BREF on);(f) the Dermatology Life Quality Index (DLQI), the application of statistical methods of the above items to draw relevant conclusions.SPSS17.0statistical software for statistical analysis of measurement data using the mean±standard deviation or median count data constitute than the χ2test, were compared with two independent samples t-test, significance level a=0.05, all The results are P<0.05as the standard that the difference was statistically significant, Identify each test level.Results:1. general clinical data survey1.1Questionnaire statistics:Nanjing, the group issued a total of190questionnaire, to recover173,155valid questionnaires were, the effective rate of89.59%. Macau group issued a total of180questionnaires to recover160,147valid questionnaires were effective rate of91.87%, Group2included in the questionnaire of302copies.1.2into the cases of Statistics:Nanjing group of cases to155cases of male patients with64cases (41.29%) female patients,91cases (85.71%), male to female ratio of1:1.42. The average age of the patients was46.49±12.72years old88years old, the maximum, minimum one month; average duration of37.57±16.41days, up to9years; average initial age of onset (years)37.49±10.14.Included in the147cases of the Macau group of cases, male patients of69cases (46.93%) female patients,78cases (53.07%), male to female ratio of1:1.13. The average age of the patients was39.60±13.01years old75years old, maximum, minimum3months; average duration of44.11±15.93days, up to7years; average initial age of onset (years)30.60±11.23. Into two groups of men and women the number of cases of sex ratio χ2test, P=0.051, no significant statistical difference. Nanjing, Macau The mean age of46.49years of age,39.60years old, by t test, P=0.011, significant differences, indicating that the eczema patients in Nanjing, Macau age distribution were significantly different, Nanjing group the average age is greater than Macao group; in the average initial age of onset, respectively, for47.49years,30.60years, P=0.021<0.05, indicating that the two groups of average initial age distribution is also a significant difference in the Nanjing group average initial age of onset is greater than the Macau group; two group the average duration of37.57days,44.11days, P=0.000<0.01, indicating that the two groups the average duration of distribution were significantly different, Nanjing group the average duration of the number of days less than the Macau group. Marital status, Nanjing group and Macau married group statistics the number of cases, respectively,97,73, two groups of unmarried patients, respectively53,61, while the two groups of widowed statistics the number of patients3,10, divorced, respectively, for2,3, Therefore, patients with single statistical number of cases the two groups were58,74, Nanjing group than in the Macau group, P<0.01, statistically significant; compared two groups of married number of cases, the Nanjing group than in the Macau group (P<0.05)(test level:χ20.05(3)=7.81; χ20.01(3)=11.34; df=3), statistically significant.2.related to epidemiological investigation2.1The loss of symmetry of the distribution of the contrast:Two groups the incidence of neck and cheek area lesions proportion compared by χ2test, Nanjing group cheek suffering from the number of cases is33, while the Macau group of18, χ2=37.645> χ20.01(10), P<0.01, Nanjing Group cheek lesions distribution was significantly higher than that of the Macau group, statistically meaningful; two sets of neck skin lesions of patients, respectively30,22, χ2=29.735> χ20.01(10), P<0.01,Nanjing carotid The rate of the Ministry of skin lesions was also higher than the Macau group was statistically significant. Two groups the proportion of incidence of skin lesions compared by χ2test, Nanjing group and Macau group in the back the number of skin lesions cases were14,10, χ2=18.793> χ20.05(8), P<0.05, Nanjing group than Macao group, statistically meaningful; the waist were13,19, χ2=30.4670.013> χ20.01(8), P<0.01, Macau group was significantly higher than that of the Nanjing group, with statistical significance; around the anus two groups14:9, χ2=28.091> χ20.01(8) P<0.01, Nanjing group higher than that of the Macau group, statistically significant. Incidence of skin lesions of two groups of proportion:the number of statistical cases of leg flexor side of the Nanjing group and Macau group were36,20, χ2=35.390> χ20.01(8), P<0.05; extensor surfaces of parts of the two groups were30,19, χ2=31.031> χ20.01(8), P<0.01, side of leg flexor and extensor surfaces of parts of the Nanjing group are higher than that of the Macau group was statistically significant; foot palm were10,17, χ2=17.839> χ20.05(8), P <0.05, the Macau group higher than that of the Nanjing group, with statistical significance.2.2lesions symmetrically distributed contrastlncidence of two groups of lesions symmetrically distributed number of cases compared by x2test, χ2=6.566> χ20.05(J), P<0.05), the Nanjing group and the diseased parts of the Macao group symmetrically significant difference P<0.01, Nanjing group was significantly higher than that of the Macau group.2.3lesions of clinical symptoms were assessed X2test of two groups of onset of lesions of the proportion of clinical symptoms, itching situation in the Nanjing group and Macau group statistics the number of cases, respectively, for47.55, χ2=13.031> χ20.05(5), P<0.05; erythema or flushing circumstances, be divided into two groups18,34, χ2=20.710> x20.01(5), P<0.01; two sets of a blister, the number of cases, respectively14,39, χ2=12.741> χ20.05(5), P<0.05, so in the emergence of itching, redness or flushing, blisters, etc., Macau group were higher than the Nanjing group; while statistics show that a hard swelling or edema of the number of cases, the Nanjing group of27was significantly higher than Macau the group17χ2=17.531χ20.01(5), P<0.01, statistically significant.2.4of patients with eczema and seasonal factors Proportion of the two groups with the seasons of incident cases by χ2test compared to the spring incidence statistics the number of cases were23,15, χ2=16.566> χ20.01(3), P<0.01, Nanjing group higher than that of the Macau group, there are statistics significance; Macau group fall, winter statistics cases, respectively10,13, Nanjing group was significantly higher than2,3, P values were P<0.01, P<0.05, the difference was statistically significant.2.5Food Factors predisposing factorsNanjing group the number of cases in the salt water products, milk and cream, fruits,23,3,4, Macau group were17,1,1, Nanjing was significantly higher than that of the Macau group, the difference was statistically significant; and eggs and egg products, wild mushrooms Macau group were7,9, and Nanjing respectively2,3, Macao was significantly higher than that of the Nanjing group, with statistical significance. Aquatic products(χ2=19.002> χ20.05(9), P<0.05; eggs and egg products χ2=22.305> χ20.01(9), P<0.01; milk and butter class χ2=19.188> χ20.05(9), P<0.05; fruit class χ2=19.563> χ20.05(9), P<0.05; wild mushrooms χ2=20.349> χ20.05(9), P<0.05)2.6environment, the material factors predisposing factorsCleaning agents, flavor factors Nanjing group statistics the number of cases were larger than for6,5Macau Group1,2, the difference was statistically significant; textiles and non-significantly induced factors, the Macau group is larger than the Nanjing group, differences There are statistically significant (detergents χ2=23.793> χ20.05(11), P<0.05; flavor χ2=20.643> χ20.05(11), P<0.05; textiles χ2=20.821> χ20.05(11) P <0.05; χ2=28.031> χ20.01(11), P <0.01).2.7eczema patients with a family history survey The two groups with a family history of incident cases, the Macao group, family history of patients was significantly higher than the Nanjing group, the difference was statistically significant (P<0.01).2.8eczema patients eating habits of life survey In alcohol, coffee and cola, hi spicy, sunbathing, sedentary, late sleeping, etc., the number of cases Macao group were higher than the Nanjing group was statistically significant; Nanjing group tea the number of cases is higher than that of the Macau group, with statistical significance.(Drinking χ2=19.635> χ20.05(10), P<0.05; drink coffee/cola χ2=27.781> χ20.01(10), P<0.01; tea χ2=20.879> χ20.05(10) P<0.05; hi spicy χ2=18.807> χ20.05(10), P<0.05; the solarium χ2=29.091>χ20.01(10), P<0.01; sedentary χ2=25.894the> χ20.01(10)P<0.01; Iate sleep χ2=20.061> χ20.05(10), P<0.05).2.9eczema in patients with occupational surveyNanjing group of medical personnel and the civil servants of the number of cases is higher than the group of Macau Macau group of teachers the number of cases of higher than that of the Nanjing group, the difference was statistically significant.(Medical personnel χ2=16.432> χ20.05(8), P<0.05; civil servants χ2=17.471> χ20.05(8), P<0.05; teachers χ2=16.002> χ20.05(8), P<0.05)2.10patients with eczema symptoms comparative survey Macau group itching-light weight aspect, statistical number of cases was significantly higher than the Nanjing group (P<0.05) difference was statistically significant; Nanjing group burning, light and heavy terms of statistics the number of cases is higher than that of the Macau group, P<0.05, significant.(Itching-light-itch-Heavy χ2value> χ20.05(5), P<0.05; burning-light-heavy χ2value> χ20.05(5), P0.05; burning-χ2value> χ20.01(5), P<0.01)2.11comparative study of patients with eczema sleep time Nanjing group for5-7hours and the number of cases of insomnia in the sleep time for102,10, respectively, higher than the Macau group77,4(P <0.05) difference was statistically significant.(More than8hours χ2=5.529<χ20.05(3), P>0.05;5-7hours χ2=8.634> χ20.05(3), P<0.05;5hours χ2=15.027> χ20.01(3), P<0.01; insomnia χ2=10.730> χ20.05(3), P<0.05)2.12eczema patients in Western medicine treatment history surveyNanjing group taking western medicine the number of cases was significantly higher than the group of Macau and Macau group did not accept Western medicine treatment, the number of cases higher than that of the Nanjing group (P<0.05) difference was statistically significant.3.the quality of life status observedDLQI score of the group of Nanjing and Macau group of patients using two independent samples mean t-test shows that the total score higher than Macau in the Nanjing group group, the difference was statistically significant (P<0.01); symptoms and emotional aspects, Nanjing The group is also higher than that of the Macau group, the difference was statistically significant (P<0.01); social communication and receiving treatment, Nanjing group, slightly higher than the Macau group, the difference was statistically significant (P <0.01). In the overall feel, physiological, psychological, social, Nanjing group were higher than Macau group, the difference was statistically significant (P<0.01).4. TCM syndromes and lesions meridian.4.1the two eczema cases modern medicine, genotyping comparison Eczema cases of the two typing comparison of modern medicine shows: Nanjing group the number of cases of both acute and chronic patients significantly more than the group of Macau and Macau group of sub-acute patients than the Nanjing group (P<0.05) difference was statistically significant.4.2the two eczema cases each card comparisonEczema cases of the two acute phase syndrome type the number of cases compared known:the number of patients than of the Nanjing group of hot and humid steeped card Macau group (P<0.05) difference was statistically significant, Spleen wet of Yun card and blood deficiency and wind dryness There was no significant difference.4.3cases of the two eczema lesions meridian distribution statistical analysisThe two cases of eczema lesions meridian distribution comparison shows:the Nanjing group Yin Meridian of Hand and foot Sanyang, the number of cases was significantly higher than the Macau group, P<0.05, statistically significant differences in lesions distribution, hands Sanyang foot yin meridians of the two groups no significant difference.Fourth, the ConclusionQuestionnaire statistics:Nanjing group issued a total of190questionnaires were to recover173,155valid questionnaires, the effective rate of89.59%. Macau group issued a total of180questionnaires to recover160,147valid questionnaires were, the effective rate of91.87%.Eczema more common in middle-aged population, no significant difference in male and female incidence of Nanjing and Macao.Eczema etiology is not clear, and should actively look for the relevant factors to guide prevention in order to reduce the recurrence of eczema. The main factors affect the quality of life of patients with eczema anxiety, dietary restrictions, illness and disease duration.3Differential Treatment with Chinese medicine, eczema, should pay attention to diagnosis the direction of the dialectic, and carefully consider the reasons of the liver, spleen, kidney imbalance, starting from the fundamental rule, when necessary, use the first rule of the underlying method to stabilize the patients mind, so as to play TCM maximum efficacy.Reflected the differences in the two patients with eczema and Nanjing and Macau eczema cases of immune function and physical differences, food culture, even the difference of the relationship of marriage in the state also play a role in the lifestyle of the law of the Macao population is obvious the crowd with the Nanjing area, this difference in the formation of considerable delay and difficulty with change. But I believe that the statistical test of differences, and not a substitute for clinical judgment, and yet can not be considered a significant difference in this topic there are specific clinical significance. Ultimately I believe that due to the existence of individual differences and sample size limitations, I hope that in the case of a conditional large sample, multi-center survey, to analyze the correlation factor of eczema.Results and Conclusion:Questionnaire statistics:Nanjing group issued a total of190questionnaires were to recover173,155valid questionnaires, the effective rate of89.59%. Macau group issued a total of180questionnaires to recover160,147valid questionnaires were, the effective rate of91.87%.1. Eczema more common in middle-aged population, no significant difference in male and female incidence of Nanjing and Macao.2. Eczema etiology is not clear, and should actively look for the relevant factors to guide prevention in order to reduce the recurrence of eczema. The main factors affect the quality of life of patients with eczema anxiety, dietary restrictions, illness and disease duration.3. Differential Treatment with Chinese medicine, eczema, should pay attention to diagnosis the direction of the dialectic, and carefully consider the reasons of the liver, spleen, kidney imbalance, starting from the fundamental rule, when necessary, use the first rule of the underlying method to stabilize the patients mind, so as to play TCM maximum efficacy. 4. Reflected the differences in the two patients with eczema and Nanjing and Macau eczema cases of immune function and physical differences related to dietary and cultural differences also play a role, the lifestyle of the general population in Macau law is obviously different from the crowd with the Nanjing areathis difference of the formation and change of considerable delay and difficulty. |
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