| Objective: observation points to thread burying polycystic ovary syndrome (PCOS)rats reproductive endocrine hormone and ovarian the morphology of the influence, toinvestigate the PCOS model of the possible role of rats mechanism, to provide the data forclinical research. Methods:24days of age female SD rats subcutaneous injectionandrogen joint human gonadotropins (HCG) made mode for the legal system in the ratmodel PCOS, the same period control injection saline. PCOS rats randomly divided intomodel group, ClomiPhene group, embedding+Clomiphene group, embedding samples,among them, the control group and the model group do not make any processing, othereach byte is in50days of age therapy since20days. After treatment, blood collection,using the united method for determination of serum serum level of each index.Experimental animals in the afternoon with the male rat6according to2:1ratio and cage,in day18of death, observing the blastocyst implantation conditions, and gather the leftside ovarian, fixed in more than4%of formaldehyde together, used as HE dyeing underlight microscopy tothe ovary influence. Results: The build, build module and significantlyhigher than the control group(P<0.05), with a statistical significance. After treatment,andmodelgroup, compared to the control group, buried, buried quad line+CC group, CCgroup weight, serum T, LH, Leptin were significantly reduced(P<0.05), all havesignificant difference; Each group FSH level difference was not significant (P>0.05), nostatistical significance. Conclusion: Meridians buried by adjusting the gonads axis linemay, in ovarian local coordination function, reduce the exceptional increasingLH and Tlevel, at the same time, reduce leptin leels, and promote the development and normalfollicle ovulation. |
PDF Full Text Request