Experimental Research On The Effect Difference Of Compound Medicine And Pure Moxibustion In Yin Deficiency Mouse

Objective:Observe compound medicine article ai ai qing and banding jiu of shenshu point model of differences in mice Yin effect to verify Chinese medicine altogether, as article--containing compound material sticks to reduce pure moxibustion side effects so as to improve the hot sticks to the effect of healing Yin deficiency exists, to develop moxibustion clinical indications to provide the basis.Methods:In the experiment and clinical observation, and on the basis of choice for18to22g (1months) health only50KM mice, female, randomly divided into a. blank group, b. model group, c. The article--dividing group, d. compound medicine article--dividing group, e. enrichment bolus of6flavour glutinous rehmannia group (strong LiuWei group), each group of10only. With thyroid element of suspension liquid filling method to establish the Yin deficiency stomach made mode. Made in7days die, die in the third day was made of shenshu point sticks, continuous sticks;5days, observe the weight of each group, and plasma ring phosphoric acid, phosphoric acid, adenosine cAMP ring cGMP content and bird cAMP/cGMP ratio.Result:1. The compound medicine article--sticks with strong group LiuWei groups of mice were significantly higher in weight model group and the article--dividing group (P<0.05); Before both between and group compared with blank there are no significant difference (P>0.05); Both group compared with blank after all significant difference (P<0.05); After comparison between them is no statistical difference (P>0.05).2. Plasma cAMP content index, model group, the article--sticks group compared with blank group were significantly increased (P<0.05); Compound medicine article--sticks, and strong LiuWei group and group is blank group there were no significant difference (P>0.05), but were significantly lower than the model group, the article--dividing group (P<0.05, P<0.01); Model group, the article--sticks comparison group, compound medicine article--sticks, and strong LiuWei group comparison group there were no significant difference (P>0.05).3. Plasma cGMP content index, model group, the article--sticks group compared with the blank group were significantly reduced (P<0.05); Compound medicine article--sticks, and strong LiuWei group and group is blank group there were no significant difference (P>0.05), but significantly higher in model group, the article--dividing group (P<0.05, P<0.01); Model group, the article--sticks comparison group, compound medicine article--sticks, and strong LiuWei group comparison group there were no significant difference (P>0.05).4. Model group, the article--sticks with blank group group compared cAMP/cGMP (P<0.01), model group and clear moxibustion no significant differences between groups (P>0.05). Compound medicine group, the article LiuWei pill sticks with group and blank group compared between and there were no significant difference (P>0.05), and model group, the article--dividing group compared cAMP/cGMP significantly reduce (P<0.01).Conclusion:1. The ai banded sticks of shenshu point Yin mice can’t play a significant role to improve, and compound medicine article ai can have good prevention and cure function. Based on the experimental mice, cAMP index weight difference is concerned, tip to join with the compound medicine containing altogether--used for the treatment of article Yin deficiency may be more suitable than ai qing article.2. Experiments show the drug sexual flavour sticks material sticks to cure effect has great effect. The experiment suggests application bitter cold of the sexual flavour gump, altogether, and bitter XinWen containing the dry YiRong blends with the production of medicine ai banding jiu, can reduce the ai banding of sexual side effects and hot sticks, make "jiu the fire" tend to be "soft".