The Preliminary Clinical Study Of Nerve-Preserving Radical Gastrectomy For Gastric Cancer

Backgrounds and objections:Gastric cancer is one of the higher morbidity and mortality worldwidetumor, accounting for four of the worldwide malignancy. Of new cases of theworld on gastric most countries, patients with an annual increase of40millionpeople, accounted for42%of the worldwide number of patients, for the secondbit of new hair malignancies, and deaths among all malignant tumors of thethird bit. The reserves the vagus nerve gastrectomy feasibility and comparisonwith traditional gastric cancer cure inter operative and postoperative quality oflife, comprehensive evaluation of reserves vagus nerve gastrectomy safety,feasibility and superiority.Material and method：To the radical gastrectomy research further reserves the fans nerves, onour hospital in February2011-2012February period by endoscopy andpathological diagnosis of gastric cancer cases of45cases studied. The envelopemethod, after the consent of their families, preoperative randomization: thetraditional group and reserves the vagus nerve group, both implemented D2surgery. By observing patients postoperatively number of lymph nodedissection, gallbladder contraction function, incidence of gallstones, theincidence of diarrhea after discharge compared to the weight, hunger and otherindicators of postoperative follow-up, follow-up points after three months andsix months period. By above study hope to be able to expand and add reservedvagus nerve gastrectomy research. Statistical analysis：The SSPS16.0statistical package for statistical analysis, the two groupsstratified chi-square test test for statistical analysis, measurement data with xGuests s, P <0.05, the difference was statistically significant.Results：Traditional group and retained the vagus nerve in patients underwent D2or D3radical mastectomy, radical was no significant difference from the viewof the range and number of lymph node dissection. And tumor stage andpathological type and tumor size, pathological type the two groups of patientshad no significant differences, and no significant differences in the generalcondition of patients. Two sets of surgical approach to gastric cancer cure wasno significant difference, and reserves the vagus nerve gastrectomy, can stillreach the radical effect. Traditional group of patients after3months and retainfans go no significant difference in neurological patients with gallstoneincidence. And follow-up after6months reserves the vagus nerve groupgallstone incidence was significantly lower than the traditional group ofpatients, and significant differences. Traditional group of patients after3months and Retention fans walk neurological patients the incidence of diarrhea,weight contrast no significant difference. After6months of follow-up foundreserves the vagus nerve group and the traditional group of patients theincidence of diarrhea, weight contrast differences significant difference.Traditional group of patients after3months and Retention fans go neurologicalpatients with no significant difference in the incidence and degree of hungereating discomfort. And after six months of follow-up found to retain the vagusnerve group of traditional eating discomfort incidence and degree of hunger,there is a significant difference, and statistically significant. Conclusions：1. Reserved fans take the nerve gastric cancer radical surgery in theanatomical structures and surgical technically is feasible, with traditionalgastric cancer radical surgery on lymph node dissection and lymph nodedissection in the number of non-significant difference, therefore retain fanswalk nerve gastric cancer radical surgery able to achieve with the traditionalgroup the radical effect.2. Reserved vagus nerve radical gastrectomy can improve the quality oflife of patients, patients with body weight increased significantly compared tothe traditional group, gallstones, diarrhea, eating low incidence of discomfortmore obvious, the last patients appetite hunger has significantly improved.Therefore, reserves the vagus nerve gastrectomy worth to explore research andpromotion.