HIV Infection And Testing Of Regular Sex Partners Among Men Who Have Sex With Men In Beijing

Background：HIV continues to spread among men who have sex withmen (MSM) on a global level. MSM contributed to about half of new HIVinfections in many Western countries. The epidemic of HIV/AIDS amongMSM in China is serious now. The complicated sexual network make MSM asignificant bridging population in the spread of HIV, syphilis and othersexually transmitted diseases from high risk population to general population.Sixty eight percent of HIV transmissions of MSM were from regular sexpartners and they play a more and more important role in the epidemic of HIVin MSM. On the other hand, HIV testing remains an important part and entrypoint of HIV prevention and care. We therefore conducted a cohort tounderstanding the prevalence and predictors of HIV among MSM in Beijing.On this basis, Rapid HIV antibody tests were offered to the respondents in thecohort to test their regular sex partners. We hope that this intervention canexpand HIV testing among regular sex partners of MSM and promote HIVstatus disclosure among MSM.Objective：1To understanding the prevalence and predictors of HIV among MSMin Beijing.2To explore the incidence of HIV among MSM in Beijing.3To understand retention rate and factors associated with retentionamong the study of MSM in Beijing.4To evaluate the effect of the offering rapid HIV test kits to respondentsfor testing their regular sex partners.5To determine the factors associated with MSM with regular sexpartners taking rapid HIV test kits.Methods：This study was conducted baseline and follow-up surveyamong MSM from July2011to July2012in Beijing. Rapid HIV antibody tests were offered to respondents with regular sex partners at baseline andfollow-up and the testing results of their sex partner were tracked. MSM wererecruited through peer referring and internet advertising. One-to-onequestionnaire interviews were conducted by using tablets to collectinformation on demographics, HIV related knowledge, sexual characteristics,etc. Blood samples were collected to examine the HIV-antibody and syphilisantibody via rapid test.SAS9.2software was used to analyze the data.Results：1Of the500MSM surveyed, the prevalence of HIV and syphilis was5.6%(28/500),26.4%(132/500),respectively. In multivariate logistic regressionanalysis, having no HIV testing in the last year or without knowing the testingresult (OR=2.57,95%CI:1.16-5.68), the age at the first sexual intercourse witha man was less than or equal to18years old (OR=2.45,95%CI:1.07-5.62) andhaving had anal intercourse with four or more male sex partners in the lastthree months (OR=2.83,95%CI:1.25-6.42) increased the risk of HIV infection.Age greater than30years old (OR=1.68,95%CI:1.13-2.52) and having hadanal intercourse with four or more male sex partners in the last three months(OR=1.83,95%CI:1.15-2.92) were independently associated with syphilisinfection.2395HIV-negative MSM were recruited in our cohort,383and348were retained at the3-month and6-month follow-up visits, and retention rateswere97.0%and88.1%respectively. Multivariate Logistic analysis revealedthat more than29years old (OR=2.08,95%CI:1.10-3.95), tested for HIV inthe past one year (OR=2.44,95%CI:1.27-4.68)were significantly associatedwith6-month retention.3Among395HIV-negative MSM,11participants seroconverted forHIV infection during205.07PY follow-up, HIV incidence was5.36/100PY(95%CI:2.19-8.53). Among288MSM test negative for syphilis antibody atbaseline,12MSM seroconverted for syphilis infection during147.55PYfollow-up, syphilis incidence was8.13/100PY (95%CI:3.53-12.73).4231rapid HIV test kits were offered to respondents with regular sex partners at baseline and follow-up.230test results were received. There are8respondents who directly took their regular sex partners to investigation scenewithout taking in rapid HIV test kits. Rate of regular sex partners tested forHIV in the past one year rose from51.7%(163/315) to72.6%(164/226)。5128rapid HIV test kits were offered to respondents with regular sexpartners at baseline. Multivariate Logistic analysis revealed that withoutfemale regular sex partner (OR=2.05,95%CI:1.05-4.00), college or abovedegree (OR=1.99,95%CI:1.10-3.60),monthly income more than3000yuan(OR=1.90,95%CI:1.09-3.32), having more than one regular sex partners in thelast three months (OR=2.12,95%CI:1.19-3.78), would have unprotected analintercourse with regular sex partners in the coming three months(OR=2.47,95%CI:1.47-4.13) and regular sex partners did not test for HIV inthe past one year(OR=2.98,95%CI:1.78-4.98) were significantly associatedwith taking in rapid HIV test kits.Conclusions：1The prevalence and incidence of HIV and syphilis among men whohave sex with men in Beijing were high and effective prevention measuresshould be taken urgently to keep down the epidemic..2Having no HIV testing in the last year or without knowing the testingresult, the age at the first sexual intercourse with a man was less than or equalto18years old and having had anal intercourse with four or more male sexpartners in the last three months increased the risk of HIV infection.3The HIV testing rate of regular sex partner of respondents risingobviously from51.7%to72.6%.We can see the application value of thisintervention strategy.4Without female regular sex partner, college or above degree, monthlyincome more than3000yuan, having more than one regular sex partners in thelast three months, would have unprotected anal intercourse with regular sexpartners in the coming three months and regular sex partners did not test forHIV in the past one year were associated with taking in rapid HIV test kits.