| Objective：Discuss joint compound ɑ-keto acid made from cordycepssinensis and optimization of protein diet on maintenancehemodialysis patients with spleen and kidney deficiency syndromeof nutritional status.Methods:1.Selected60patients were2012.3-2013.3in hospital bloodpurification center of hubei province hemodialysis treatment, andcan be diagnosed cases of spleen kidney deficiency.The selectedpatients were randomly divided into two groups, control group andtreatment group of30cases each.Control group given compound ɑ-keto acid and fish、meat、eggs、milk quality protein diet;treatmentgroup in the control group on the basis of fermentation cordycepssinensis powder.Two groups of cases in age, sex, dialysis time,assay index, primary disease, dialysis parameters (Kt/V of1.2orhigher), etc. there is no obvious difference of comparative (P>0.05),two groups of data are comparable.2.After into the group,diet education carried out byresearchers or nurse to the patient,Including diet, how to fill out the food diary,2days before the visit record (namely dialysisperiod) between the body measurements,at the same time forlaboratory inspection,measured nutrition indicators including BMI,grip strength, propagated, Hb, PA, TG, CHO, CRP;Blood biochemicalindexes including blood Scr, blood calcium, phosphorus,potassium,And record the patients clinical symptoms of traditionalChinese medicine integral.Control group given away with0.075to0.12g/kg/d (630mg/piece,one piece every5-8kg weight),andoptimization of protein diet(by the doctor according to patientcondition to the prescription of0.8to1.2g/kg/d proteinintake,about50%of high quality protein,energy intake guarantee30-35kal/kg/d),treatment group on the basis of the control groupto the fermentation cordyceps sinensis powder,1.0g/time,3times/day,observation period for patients with continuous dietguidance.After3months review,to observe the curative effect ofnutritional therapy in patients with integral to make curativeeffect assessment of traditional Chinese medicine (TCM) andclinical symptoms.3.Analysis using SPSS13.0statistical software for datastatistics processing,using t test, measurement data are expressedas a x±s,count data using x2test.Results:1.Nutrition indicators：Comparison in the group,TG, CHO, thetwo groups after treatment than before treatment were significantlyimproved,statistically significant difference (P<0.05);treatmentgroup after treatment propagated, Hb, CRP and PA is before treatmentwere significantly improved,statistically significant difference(P<0.01);In the control group after treatment of Hb, CRP was were significantly improved, the difference has statisticalsignificance (P <0.01);ALB in the control group after treatmentthan before treatment significantly improved,statisticallysignificant difference (P <0.01);the control group PA than beforetreatment significantly improved after treatment,statisticallysignificant difference (P <0.05).Comparison between groups:Aftertreatment the treatment group propagated, PA is superior to thecontrol group,statistically significant difference (P <0.01).2. Nutrition indicators：The two group after treatment of bloodcalcium values is improved than before treatment,statistically significant difference(P<0.05),The two group aftertreatment the blood phosphorus value was obviously improved,Statistically significant difference (P<0.01).3.TCM clinical symptom integral comparison before and aftertreatment: Within the group to compare:The control group aftertreatment of traditional Chinese medicine clinical symptomintegral score was improved, Statistically significant difference(P<0.05),Treatment group after treatment of traditional Chinesemedicine clinical symptoms integral score before treatmentsignificantly improved,statistically significant difference (P<0.01).Comparison between groups,Treatment group after treatment oftraditional Chinese medicine clinical symptom integral scores thanthe control group improved significantly， statisticallysignificant difference(P<0.01).4.Before and after treatment of TCM symptoms curative effectcomparison: Effective rate of treatment group after treatment ofTCM symptom of83.33%,The control group after treatment symptomsof TCM effective rate was56.67%,Compared two groups of curative effect said there were significant differences statisticallysignificant data,The treatment group is superior to the controlgroup (P<0.01).Conclusion:Joint compound ɑ-keto acid made from cordyceps sinensis andoptimize propagated protein diet can not only improve maintenancehemodialysis patients, PA, Hb, blood calcium, TG, CHO, CRP, bloodphosphorus,And in improving the propagated, PA applicationssimpler compound ɑ-keto acid effect is more obvious.Treatmentresults showed the nutritional status of patients, blood lipidmetabolism, calcium phosphorus metabolism and inflammatory statushas improved significantly,And can effectively relieve patientslanguid, lumbar debility, less food, stay, clinical symptoms suchas shortness of breath lazy said. |
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