The Application Of Pentacam In The Diagnosis Of Primary Angle-closure Glaucoma Diagnosis And The Efficacy Evaluation Of Laser Peripheral Iridotomy

Objective: Measure the anterior chamber parameters of the normal andthe primary angle-closure glaucoma (primary angle-closure glaucoma, PACG)with Pentacam anterior segment analysis system integrated3D: anteriorchamber depth (ACD), anterior chamber volume (ACV), the anterior chamberangle (ACA). To seek the methods for early screening of primaryangle-closure glaucoma. With Pentacam anterior segment analysis systemintegrated3D to measure the changes in anterior chamber morphologicalparameters before and after the incision in the primary acute angle-closureglaucoma preclinical eyes and the primary chronic angle-closure glaucomacontralateral eye laser peripheral iris, looking for the sensitive indicators of theanterior chamber morphological changes and to evaluate the efficacy of laserperipheral iridotomy surgery.Methods:125eyes of normal control group,25eyes of primary acuteangle-closure glaucoma remission,25eyes of primary chronic angle closureglaucoma,25eyes of primary acute angle closure glaucoma in the preclinical,25eyes of Primary chronic angle-closure glaucoma contralateral, apply thePentacam anterior segment three dimensional analysis system formeasurement of anterior chamber parameters: anterior chamber depth(anterior chamber depth, ACD), anterior chamber volume (anterior chambervolume, ACV), the anterior chamber angle (anterior chamber angle, ACA).2Apply the Pentacam anterior segment analysis system of3D to measureanterior chamber parameters of the primary acute angle-closure glaucomaclinical eye laser peripheral iridotomy at the1days,7days,28days beforeand after the incision: anterior chamber depth (ACD), anterior chambervolume (ACV) the anterior chamber angle (ACA).3Apply the Pentacam anterior segment analysis system of3D to measure anterior chamberparameters of the primary acute angle-closure glaucoma clinical eye YAGlaser peripheral iridotomy at the1days,7days,28days before and after theincision: anterior chamber depth (ACD), anterior chamber volume (ACV) theanterior chamber angle (ACA).4Calculate the anterior chambermorphological parameters change before and after the incision in the primaryacute angle-closure glaucoma preclinical eye laser peripheral iris: the anteriorchamber morphological parameter values measured28days later-the anteriorchamber morphological parameter values measured28days ago.Results:1Normal control group and remission of primary acuteangle-closure glaucoma, primary chronic angle-closure glaucoma, primaryacute angle-closure glaucoma preclinical contralateral eye comparison ofprimary chronic angle-closure glaucoma, the three parameters values of theanterior chamber morphology measured in normal controls group are greaterthan that in other groups, the differences were statistically significant (P<0.05). compare the groups of Primary angle-closure glaucoma, the differencewas not statistically significant.2After the Primary acute angle-closureglaucoma preclinical eye laser peripheral iridotomy postoperative, the depthand the anterior chamber volum become larger compared with thepreoperative,the difference was statistically significant (P <0.05).the anteriorchamber angle between the value of preoperative difference was notstatistically significant. after1day,7days,28days, anterior chamber depthvalues, values of anterior chamber volume, anterior chamber angle betweenthe comparison, the difference was not statistically significant.3Postoperativetime points anterior chamber depth compared with primary chronicangle-closure glaucoma the contralateral eye laser peripheral iridotomydeepened anterior chamber volume compared with the preoperative was larger,and the difference was statistically significant (P <0.05);anterior chamberangle between the value of preoperative,and the difference was notstatistically significant after7days,28days and one day after the anteriorchamber depth, anterior chamber volume comparison, the difference was statistically significant (P <0.05); surgeryafter7days,28days, anteriorchamber depth, anterior chamber volume comparison, the difference was notstatistically significant. Postoperative time point of the anterior chamber anglebetween the value of the comparison, the difference was not statisticallysignificant.4Primary acute angle-closure glaucoma preclinical eye laserperipheral iridotomy postoperative anterior chamber depth added value (28days after anterior chamber depth-preoperative anterior chamber depth), theincrease in value of the anterior chamber volume (after28daysanteriorchamber volume-preoperative anterior chamber volume) significantlyincreased compared with the contralateral eye of primary chronicangle-closure glaucoma, the difference was statistically significant.Conclusions:1Pentacam anterior segment of the three-dimensionalanalysis system for measuring the anterior chamber of morphologicalparameters can provide the basis for the screening and early diagnosis ofprimary angle-closure glaucoma.2Pentacam anterior segment of thethree-dimensional analysis system can be used to quantifily evaluate changesin the morphology of the anterior segment laser peripheral iridotomypostoperative, to provide a reference for the assessment of prognosis.