| Nanochannel is the pore or tubule with diameter from0.1to100nm.Because of its three unique effects, the surface effect,size effect andmacroscopic quantum tunneling effect, it is exhibiting a great potentialadvantage and a good prospect in physical chemistry, materialsscience, biomedical and other applications. In recent years,nanochannel has many stages of research results in the substancesseparation, detection, DNA sequencing. This paper started from thepreparation, modification of the gold nano-channel,studied themigration mechanism of environmental pollutants and the separationof these substances by nanochannel technique.Bisphenol A (BPA) is one of the most widely used industrialcompounds in the world.It is everywhere from water bottles, medicaldevices to food packaging. BPA is an environmental endocrinedisruptors that can lead to endocrine disorders,cancer, andmetabolism-induced obesity. The traditional analysis methods ofBisphenol A rely on high performance liquid chromatography, gaschromatography-mass spectrometry, liquid chromatography-massspectrometry and so on.Contrast to these analysis methods,nanochannel technology is more effective and has betterperformance. Details are presented in this work as follows：(1) An electroless deposition method was used to deposit gold aperiod of time within the pores of the polycarbonate templatemembrane and gold nanochannels with different diameters wereobtained. Scanning electron microscopy (SEM), transmission electronmicroscopy (TEM) were used to characterize the pore size and thesurface appearance.Uniform and reliable gold nanochannelsmembranes can be obtained in this way.(2) Gold nanochannal have been modified with different substance to change their hydrophobicity. Separation of hydrophobicsubstance were investigated by studying the migration rate ofbisphenol A and progesterone in the gold nanochannel. Because thedifferences structure of bisphenol A and progesterone result inmigration rate different in gold nanochannel, bisphenol A andprogesterone can be separated.(3) L-cysteine was modified onto the gold nanochannels to renderthe nanotubules chiral and enantioselective behaviour for adsorptionof chiral molecules. The migration of D-tryptophan and L-tryptophanthrough gold nanochannel and the effects of pH and porediameter of tubules on the separation for these two substances werediscussed. We can expect to provide some theoretical support for morewidely practical application on enantiomers separation ofnanaochannels. |
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