| At present, the choice pressures caused by antibiotics cause the increase of the antibiotic resistance and the diversification in resistant bacteria and resistant mechanism, they are severe test to human antiinfection treatment[1]. On the other hand, wastewater and medical wastewater containing antibiotics pharmaceutical are discharged into environment. As well as agricultural use of livestock excreta containing a large number of antibiotics, which directly cause the damage of environmental microbial ecosystem. Mean while because of the long-term antibiotic residues may cause Microbial resistance changes in the environment such as soil environment.In this paper, the integrated use of traditional methods of soil chemistry and microbial ecology research tools, and learn from the environmental impact assessment method, analysis of antibiotic residues in livestock and poultry free-range drug resistance bacteria and the resulting environmental impact of pollution; antibiotics into the soil environment, on microbial ecology and environmental impact of microbial drug resistance; and the resistance bacteria on the initial spread of pollution control were discussed. The results are as follows:1. Tetracycline at the3soils (high sand influx soil, paddy soil, waste of the Yellow River alluvial sandy soil) in the adsorption conformed to Freundlich model and Langmuir model, two models showed a good linear relationship as belonging to physical adsorption process. There is a big difference in soils about adsorption of tetracycline, calculated by the Langmuir equation3the maximum adsorption capacity of soil of tetracycline (Qm value) were sandy loam817.7mg/kg, loam1057.4mg/kg and sand188.7mg/kg, the same trend with the Kf value. Both highly significant (p≤0.01), correlation coefficient r was0.997. Soil properties on adsorption of norfloxacin major impact of soil pH was highly significant and negative correlation, the relationship with other properties is not obvious. 2. Through the soil column on the outdoor culture of data analysis, we found the environment by adding a certain concentration of antibiotics, the formation of antibiotic stress environment, the soil will increase the number of resistant bacteria. Environment and natural degradation of antibiotics in the role of leaching look, continue to lower the concentration, the soil will decrease the number of resistant bacteria, but there are hysteresis, and the higher the concentration, the more obvious the longer the duration.3.By reading literature and field observation, the use of environmental impact assessment methods and large-scale backyard poultry farming characteristics of the two farming methods, antibiotics and antibiotic use and management characteristics of the environmental impact of pollution in the analysis, and make weight analysis table. Found that livestock farming is a major retail antibiotic resistance caused by pollution and an important source of bacterial contamination, compared to large-scale farming more easily cause harm to human health.4. Antibiotic residues in soil by adsorption in the migration, as well as antibiotic resistant bacteria under stress changes in the results of the research community and reading the literature, we found that commonly used antibiotics such as tetracycline, oxytetracycline, norfloxacin, etc. are higher soil pH value of the weak adsorption and bacterial antibiotic resistance decreased with the environment and the weakening of the characteristics of alkaline leaching through the soil residues of antibiotics, reducing closely related to human activities of antibiotics in the upper soil content, to weaken or eliminate one of the resistance gene. Experimental results show that alkali leaching can quickly reduce the concentration of antibiotics in soil, reducing the role of antibiotics, stress, thereby reducing the soil resistance gene in the human health threat. |
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