On The Basis Of The Experience Of Traditional Chinese Medicine Literature Mining Analysis Of The Clinical Dosage Of Strategy Research

Objective:The classical prescription is the prescription of Zhang zhongjing of Eastern Han, it has the feature of formulating rigorous, accurate and effective. Until now, it still be widely used by doctors. However, with the change of weights and measures, the drug dosage of the classical prescription has become a mystery, which led to the discuss about the dose. Chinese medicine does not pass the secret lies in the dose, but the dose is precisely the key to influence the clinical efficacy. How to control the dose has become a topic to discuss, meanwhile, Chinese literature research is an effective way to explore the prescript ion dose. This study was designed to elaborate the clinical strategies by the data mining analysis and some personal ized clinical strategies on the basic of the ex per ience of tutor Tong. After all, we want to make the strategies scientific, rigorous, and lay a solid foundation to improve the clinical efficacy.Research Methods and results:Through the clinical literature of the past10years, the analysis of the case, and the tutor’s personalized experience, we can obtain some effective clinical dosage strategy.1. The research of the clinical dosage strategy based on the Nearly10years of clinical experience literatureThrough the CNKI, by the use of "classical prescription" merge "experience" as the key words, I retrieved473studies. By screening, classification, summary, refining, and brainstorming methods, I summarized six clinical dosage strategies, which are "when the efficacy be seen, we can reduce the dosage"," when the efficacy is significant, we have to increase the dosage","if the dosage is too little to cure the disease, we have to increase the dosage"," the proportion of the drugs is the key of the compatibility of medicines"," the dosage is advised to be reduce when the patient’s stomach is uncomfortable.", and "great amount of drugs can direct to the lesions quickly". As each of the dosage strategies based on the literature, it’s scientific, and can be text on clinic.2. The clinical application of the six strategiesElaborate the six strategies one by one by the use of the experience case, in order to understand how to use them on the clinic easily. 3. Professor Tong’s personalized strategiesAs we pay attention to the common law, personality can’t be ignored. So we summarized Professor Tong’s experience and conclude that1liang in the classical prescription proximately equals to15g, we also summarized some personalized strategies:" when the patient’s condition is critical, we have to use big amount of the drug","take the medicine exact can ensure safety","we can use decoction first to cure the disease and take pills to nurse back to health","we should be bold but cautious about the compatibility and decoction". After all, I used case to analysis each of them one by one in order to get the treatment ideas of the acute and critically ill patientsThe resultsThe dosage strategy of the classical prescription is a new idea to guide how to control the clinical dosage. It’s an important part of the study on the relationship of the dosage and the efficacy. By the way of the literature study to summarize the dosage strategy is a new issue of the Data Mining area. The six dosage strategy we got from the past10years’literature, which were "when the efficacy be seen, we can reduce the dosage"," when the efficacy is significant, we have to increase the dosage","if the dosage is too little to cure the disease, we have to increase the dosage"," the proportion of the drugs is the key of the compatibility of medicines"," the dosage is advised to be reduce when the patient’s stomach is uncomfortable.","great amount of drugs can direct to the lesions quickly", and the four we got from Professor Tong, which were "when the patient’s condition is critical, we have to use big amount of the drug","take the medicine exact can ensure safety","we can use decoction first to cure the disease and take pills to nurse back to health","we should be bold but cautious about the compatibility and decoction" can provide an important reference for clinical usage. Although this amount of strategies is concluded through the research of the classical prescription, is universal.