| The dosage is the soul of prescription, is the edge of doctors, affect curative effect, life and death of traditional Chinese medical science. Nowadays, setting standard about dosage of traditional Chinese medicine is lack of conscientiousness and scientific. The dosage of clinical prescription and standard stated dosage have large deviation. Dosage, which the reason of Traditional Chinese Medicine didn't spread, is a secret. Classical prescription, which is the paragon of Traditional Chinese Medicine prescription, which spread up to now, the reason of spread is Classical prescription's effectiveness and practicality. With generation has changed, metrology changed, dosage's problems become the focus of Chinese Medicine. Research the problem of Classical prescription's dosage from representative doctor Cao Yingfu who was worth commend in modem history. Excavate, analyse, conclude and sum up Cao Yingfu's typical dosage of regularity. It has guiding significance for dosage of conversion, guiding for clinical using high-dose medicine, poison medicine and utility fierce medicine. To provide more specific and accurate reference for the present standard dosage which setting in pharmacopoeia and traditional Chinese medical textbook. Development of TCM dosage has important practical significance for improving TCM clinical effects, inheriting and carrying forward zhongjin medicine.Based on the present research Classical prescription's dosage and Cao Yingfu's current research situation, indicate research Classical prescription's dosage is very important, indicate research about representative doctor Cao Yingfu's typical dosage of regularity is very necessary. The main research contents and conclusions are as follows:One:sum up Cao Yingfu prescription's dosage of unit:sum up all related unit from works《Classical prescription's experience record》and《Cao Yingfu's case record》Two:research about prescription's dosage of Cao Yingfu in common use.(one) statistics analysis all frequency of occurrence medicine in 174 prescriptions, make icon, sum up medicine which frequency more than 14 times.(tow) classify by different frequency of dosage, make icon, obtain every medicine's maximal dose,minimum dose. Statistic in details, calculate the values which frequency appear between 25%-75%, that value is range of dosage.Three:compare Cao Yingfu's dosage with zhongjin's dosage and dosage in pharmacopoeia and traditional Chinese medical textbook.(one)compare with zhongjin, can obtain the discipline that Cao yingfu's dosage roughly follow "past dosage used in 3 liang, now use in 3 qian",and there has related description, from that description we know that One tenth of the conversion ratio is about "a dose of medicine". Explain and extinguish promiscuous parlance "a day dose" and "a dose" (tow) compare Cao Yingfu's dosage with dosage in pharmacopoeia, Cao Yingfu's range of dosages are large in pharmacopoeia and traditional Chinese medical textbook.Four:research about Cao Yingfu's poisonous dosage. List fuzi, wutou, xixin, put this situation contact with clinical, raise thinking about poisonous dosage. These ideas will point our secure medicate.Five:research about CaoYingfu's maximal dose. Cao Yingfu often use huge dosage medicine, for instance:Shengshigao's dosage used in 2 jin, Chuanxiong's used in 1 liang, shengdahuang's used in 1 liang, Shengdangsheng's used in 2 liang, Jinhuangqi's used in 2 liang, Chishao and Baishao each dosage used in 1 liang. Analyze these medicine's using situation, analyze each case. Cao Yingfu often cure critical disease using maximal dose medicine, and using maximal dose always given amount added gradually inverse.Six:research about Cao Yingfu's drastic medicine dosage, (one) from the theory of medicine. List Mahuang, in CaoYingfu's early years,using dosage in Mahuang were only 1 qian, dosage is lighter, after using three to five dosage, and pay special attention to between different situation, (two) From the theory of prescription, Cao Yingfu used Dachengqitang, the dosage of soup of Dahuang between 3 qian to 5 qian, the dosage of Zhishi often 3 qian or 4 qian, Mangxiao's dosage often 2 qian or 3 qian. Accurate dose makes a effective drugs. Cao Yingfu used Daxianxiongtang, the dosage of soup of Shenchuanjun 5 qian,Zhigansui 2qian, Xuanmingfen 3 qian. And the gradual increase dosage should not impatient(three) From the theory of disease, Cao Yingfu applications for shizaotang to cure phlegm retention, for Didangtang to cure hemorrhage disease, arise from the dead.Seven:Other doses of the law:(one) maximal dose medicine was used gradually increase from little dosage. (two) Dose compatible with the disease.(three) Dose of light and severe illness, it difficult to eliminate the disease.(four) New disease on the effective use of light dose, chronic disease with high-dose therapy is also difficult to cure. (five) Powder into water to cook, the result is not obvious effect (six) Featured dose:Guizhi 4 fen Guizhi cure nucha carbunde.Tinli Cao Yingfu use several fen, but contemporary use less. Weijin Cao Yingfu's maximum dose with 5 qian. Sendi's dose in Zhigancao soup at least 6 qian, Guizhi's dose at least one and half qian, this dose can be effective. This follows seven of the party drug Yin, Yang-third of drugs, medicine for the body of Yin and Yang for the use of drugs significance.Cao Yingfu rules of these doses of drugs on our clinical usage has many inspirations, how medication safety, how to choose the amount syndrome, the condition of the priorities, the patient's age, physical, drug formulation, boiling time and the impact of the dose used, these are we need to continue and in-depth a specific study. The dose research is a long and far-reaching. As a new generation of Chinese medicine, we must learn in Jhongjing more effort, more clinical experience and more practice, more exploration, and gradually realize the magic dose effects caused by changes. |
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