| Research purposes:Treatment of spleen deficient by applying the method of regulate spleen and stomach wet type obstruction of heartache (stable angina), by observing the patient’s survival quality, clinical symptoms improved and the related physiological indicators, to observe the clinical effect of this method.Research methods:There are60cases in this study, It is divided into treatment group30cases,30cases of control group by the random number table. With reference to the ministry of health of the Peoples Republic of China in2002set "Chinese traditional medicine new drug clinical research guiding principle" issued by the relevant provisions of the accord with diagnostic criteria of traditional Chinese medicine (TCM) and western medicine stable angina obstruction heartburn, for it in the standardization on the basis of conventional western medicine treatment, the treatment group to the spleen expectorant medicine granules treatment, the control group only give standardized routine western medicine treatment. Continuous dosing28days (4weeks).Results:After4weeks of clinical observation, through the statistical analysis of the indicators, the results showed that:1. in improving TCM symptoms curative effect:Treatment group and control group total effective rate was86.67%and86.67%respectively, the total effective rate in treatment group is better than that of control group, but comparison between groups (P>0.05), no statistical difference.2. Chinese medicine symptom classification quantization table total score:Treatment group comparison before and after therapy (P=0.016, P<0.01. compared before and after therapy the control group (P=0.011, P<0.01, in comparison of before and after treatment group were statistically significant.Comparison between groups before treatment (P=0.571, P>0.05, no statistical difference; Comparison between groups after treatment. P=0.029, P<0.05. statistically significant, the treatment group curative effect is better than the control group.3. Each item of traditional Chinese medicine symptom curative effect changes:In the two groups after treatment, the Chest tightness, fatigue weakness, lumbar debility, insomnia, spontaneous perspiration, the total effective rate between groups is statistically significant that the curative effect of treatment group is better than the control group; Chest pain, shortness of breath, palpitations, total efficient is no statistical difference between groups, but the total effective rate in treatment group was higher than the control group. 4. In the aspect of ECG total effective rate:Treatment group and control group total effective rate of ECG was73.33%and73.33%respectively, the total effective rate of treatment group was higher than the control group, but comparison between groups (P>0.05), no statistical difference;5. In the aspect of improving heart rate:Reduced heart rate are both two groups after treatment, the treatment group before and after treatment comparison (P=0.027, P<0.05, before and after treatment comparison the control group (P=0.039. P<0.05, suggesting that both groups have a slow heart rate, reduce the role of myocardial oxygen consumption.Before and after treatment, between the two way comparison (P>0.05), no statistical significance.6. In terms of nitroglycerin stopped reduction rate:Treatment group and control group of nitroglycerin stopped reduction rate were85.00%and72.22%respectively, the treatment group of nitroglycerin stopped reduction rate is higher than the control group, but comparison between groups (P>0.05). no statistical difference;7. In Seattle angina questionnaire total score:Treatment group before and after treatment comparison P=0.008, P<0.01, before and after treatment comparison the control group (P=0.006, P<0.01. suggesting that two groups of patients after treatment, angina questionnaire was to reduce the total integral;Comparison between the two way before treatment (P=0.486, P>0.05, no statistical difference; After treatment between the two way is P=0.036, P<0.05, suggesting that the treatment group curative effect is better than the control group.8. The Seattle angina questionnaire before and after the treatment of various dimension integral:Before the treatment, two groups of patients with angina questionnaire each dimension integral comparison had no statistical significance (P>0.05):After treatment:limited physical activity level and disease awareness within the group of comparison and contrast between groups have no statistical significance (P>0.05); Stable angina pectoris degree within the group, and compared between groups had statistical significance (P<0.01). the treatment group were better than control group; Angina pectoris attack and treatment satisfaction with aspects of the contrast group were statistically significant (P<0.01). the comparison between groups (P<0.05), treatment group curative effect is better than the control group. |
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