| ObjectiveTo observe the clinical effect and discuss the mechanism of treating Stable Angina Pectoris from the spleen and stomach.MethodsThe research is divided into two parts.The first part is to observe the clinical effect of Tiaopiyixin decoction on treating stable angina pectoris. Sixty patients of stable angina pectoris were divided randomly into Tiaopiyixin decoction group (treatment group) and Xuefuzhuyu decoction group (control group), 30 cases in each. Both groups were given the decoction for 4 weeks. The changes of clinical symptoms, ECG and treadmill exercise test in all patients were observed before and after treatment.The second part is to observe the clinical effect of Tiaopihuayu particles on improving stable angina pectoris, and the effect of traditional Chinese medicine on patients with coronary heart disease quality of life. Forty-eight patients of stable angina pectoris were divided randomly into Tiaopiyixin particles group (control group), Xuefuzhuyu particles group (control group) and Tiaopihuayu particles group (treatment group), 16 cases in each. All patients were all given the treatment for 8 weeks. The changes of clinical symptoms, ECG, treadmill exercise test and the quality of life indexes in all patients were observed before and after treatment.Results The results of the first part: Tiaopiyixin group and Xuefuzhuyu group can both significantly improve the clinical symptoms, and there were significant difference between the beginning and the end of the trial in both groups (P<0.05). The total effective rate of two groups were respectively 70.00%, 73.33% (Tiaopiyixin group) and 66.67%, 66.67% (Xuefuzhuyu group) in relieving main symptoms and total symptom, but there was no significant difference between the two groups (P>0.05); the ECG total effective rate of two groups were respectively 63.64% (Tiaopiyixin group)and 80.0% (Xuefuzhuyu group); in improving treadmill exercise test, the total effective rate of two groups were respectively 51.9% (Tiaopiyixin group) and 56.0% (Xuefuzhuyu group).The total effective rate of Huoxuehuayu group were better than those of Tiaopiyixin group but no significant difference in ECG and treadmill exercise test(P>0.05). All these indicate that the two groups can both improve the clinical symptoms and ECG, treadmill exercise test indexes, but the Tiaopiyixin decoction has more advantages on relieving clinical symptoms.The results of the second part: Three groups can all significantly improve the clinical symptoms, and there was significant difference between the beginning and the end of the trial in three groups (P<0.05). The total effective rate of three groups were respectively 87.5%, 68.8% (Tiaopiyixin group); 87.5%, 87.5% (Xuefuzhuyu group) and 75.00%,62.5% ( Tiaopihuayu group )in relieving TCM main symptoms and total symptom, but there were no significant difference in the three groups (P>0.05); the ECG total effective rate of three groups were respectively 40.0% (Tiaopiyixin group),75.0% (Xuefuzhuyu group) and 60.0%( Tiaopihuayu group), there was no significant difference among the three groups; the total effective rate of three groups were respectively 73.3% (Tiaopiyixin group), 66.7% (Xuefuzhuyu group) and 81.3% (Tiaopihuayu group), but no significant difference in improving treadmill exercise test (P>0.05).All these indicated that three groups can all improve the clinical symptoms and ECG, treadmill exercise test indexes, but the Tiaopihuayu group has more advantages on improving ECG and treadmill exercise test indexes, compared with the Tiaopiyixin group.Conclusion 1 The Huoxuehuayu group has advantages, in improving myocardial ischemic indicators of ECG and treadmill exercise.2 Compared with Huoxuehuayu group, the Tiaopiyixin group has an advantage for the improvement of clinical symptoms, especially in the non-specific indicators and improving the quality of life indicators.3 Tiaopihuayu group has the most advantages in relieving chest pain and improving the indicators of treadmill exercise tolerance.
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