Study On The Synthesis And Catalytic Activities Of Polyethylene Glycol-bound Sulfonic Acid And Graphene Oxide

Ecological environment and social resources have become the focus of the worldwith the progress of society. Environmental economics has become an importantsteering wheel for technological innovation. Chemical workers are also put forwardhigher request, requirement accord with the concept of green chemistry synthesis,which is the atom economy reaction, without the use of harmful catalyst and solvents,etc. It makes the environmental protection is no longer a new way of treatment afterpollution.Basing the review about solid-phase synthesis with simple separation. theliquid phase organic synthesis supported by the solution macromolecularpolyethylene glycol（PEG）with the stability of the homogeneous reaction efficiency,which has advantages of easy separation. Herein, on the basis of introduction ofsupported acid catalyst in organic synthesis research progress, the synthesis andcatalytic activities of Polyethylene glycol-supported sulfonic acid catalyst andgraphene oxide were studied. Three chapters are included in thesis.1. The supported acid catalysts in organic synthesis are reviewed.2. PEG-OSO₃H was used as an excellent catalyst for Mannich to give β-Aminocarbonyl compounds in PEG400/H₂O. This method has advantages of eco-friendlydegradable, highly activity, highly stable and recycling of catalyst. Benzoxanthenesand2H-indazolo[2,1-b]phthalazine-triones were synthesized by PEG-OSO₃H undersolvent-free condition. Thesis synthesis methods have the advantages of fast reactionrate, high selectivity, simple work-up and recycling of catalyst.3. PS-PEG-OSO₃H was prepared and characterized by FTIR, TGA, XRD, SEMand XPS. Its application in the Mannich reaction was studied in water medium atroom temperature and12β-amino ketones compounds were afforded. This methodhas advantages of short reaction time, high yields, simple operation and recycling ofcatalyst.4. Graphene oxide was used as an excellent catalyst for the reaction of analdehyde/ketone and two indoles to give3,3-bis（indolyl）methanes under water medium and at room temperature. As a solid catalyst, GO is easily available, cheap,environmentally benign and recycling of catalyst.