Study On The Monitoring Method Of Volatile Organic Compounds (VOCs) From Typical Pharmaceutical Industry

The pharmaceutical industry is one of the main pollution sources of VOCs. At present,there is no discharge standard of VOCs for pharmaceutical industry in our country, there isno corresponding standard system either, so it is necessary to study on analysis methods ofVOCs monitoring of pharmaceutical industry.Based on the VOCs emission characteristics of typical pharmaceutical industry, themethod for the determination of acetone, ethyl acetate, ethanol, isopropyl alcohol, benzene,toluene, ethyl acetate and n-butanol was established. The VOCs were sampled byactivated charcoal adsorption, desorpted by carbon disulfide and qualitatively analyzedand quantitatively detected by capillary column gas chromatography. All the eightcompounds were sampled and analyzed at the same time and had a good separationperformance in the fixed condition. The correlation coefficients of the calibration curvewere greater than0.999and satisfied the need of quantitative and qualitative analysis ofthe eight VOCs. The relative standard deviation was between1.0%~3.2%; the recoveryrate were between90.5%and102.9%;and the detection limits were between0.0018mg/m3and0.0084mg/m3. All the performance parameters reached the standard requirement andwere equivalent to the national standard. The desorption efficiency of the sevencompounds were between85%~103%except ethanol. And it could meet the nationalstandard which was above75%. The desorption efficiency of ethanol is lower than75%,so the determination results of ethanol was for reference only. This Method was suitablefor the determination of VOCs of the stationary source emission and unorganized emissionin the boundary of typical pharmaceutical industry.Simultaneously, The samples were collected in SUMMA Canister. The VOCs werequalitatively analyzed and quantitatively detected by air pre-concentration and gaschromatography-mass spectrometry for the thirty-nine kinds of VOCs. It hada good separation performance in the fixed pre-concentration and gaschromatography-mass spectrometry condition. The correlation coefficients of thecalibration curve were greater than0.99and satisfied the need of quantitative andqualitative analysis; the relative standard deviation is between1.4%~6.8%; the recoveryrate were between82.3%and113%, and the detection limits were between0.08μg/m3and1.74μg/m3. All the performance parameters reached the standard requirement and wereequivalent to or better than the national standard. The sampling time could be several minutes to24hours by SUMMA canister and the sample could be stored for10days atleast. This method could be used for the trace analysis of the TVOC in the ambient air andwas suitable for the monitoring of the unorganized emission in the boundary ofpharmaceutical industry.