Assessment Of Left Ventricular Systolic Dyssynchrony In Patients With Chronic Heart Failure By Quantitative Tissue Velocity Imaging Jointed With Two Dimensional Speckle Tracking Imaging

Objective Based on the left ventricular (LV) systolic dyssynchronous parameters fromrecent studies, the aim of this study was to assess the LV systolic dyssynchrony in patients withchronic heart failure (CHF) in the LV long-axis longitudinal motion by quantitative tissuevelocity imaging (QTVI) and LV short-axis radial motion by two dimensional speckle trackingimaging (2D-STI). With further, to offer the important reference informations for clinic by theway of quantitatively locating the LV systolic dyssynchronous segments in patients with CHFbefore CRT and hopefully to guide the location of pacing site. Methods38patients withCHF were enrolled in this study as study group and32subjects were selected as control groupwho were respectively performed QTVI and2D-STI examinations. The time to peaklongitudinal myocardial systolic velocity（Ts）were measured in6basal segments and6middle segments by QTVI from the apical four-chamber, apical two-chamber and LV long-axis views respectively, while the time to peak radial strain (Ts) were measured at the papillarymuscles level by2D-STI from the LV short-axis view. The maximal temporal difference of Ts(Ts-dif) and the standard deviation of Ts (Ts-SD) were calculated respectively. Results①There was no significant difference in control group of Ts between long-axis longitudinal12segments measured with QTVI and short-axis radial6segments measured with2D-STI (P＜0.05).②Ts measured withQTVI and2D-STI was significantly longer in CHF group than thatmeasured in control group(P＜0.05)，meanwhile dyssynchrony index Ts-SD and Ts-dif weresignificantly longer in CHF group than that calculated in control group (P＜0.05).③There wassignificant difference of the consistency of the most delayed systolic LV segments in patients with CHF in long-axis longitudinal detected by QTVI and short-axis radial detected by2D-STI.Conclusions①Both QTVI and2D-STI could quantitatively assess the LV systolicdyssynchrony in patients with CHF.②There was systolic dyssynchrony in patients with CHFeither in LV long-axis longitudinal motion or in LV short-axis radial motion.③There wasinconsistency in the detection rate of the LV systolic dyssynchrony in patients with CHF eitherin LV long-axis longitudinal motion by QTVI or in LV short-axis radial motion by2D-STI; aswell, there was inconsistency in the most delayed systolic segments measured with the twotechniques. As a result, it is of clinical significance to joint the two techniques together toassess the LV systolic dyssynchrony in patients with CHF.