The Relationship Between Insertion Amount And Effectiveness Of Bone Cement In Unipedicular Percutaneous Vertebroplasty On Treating Osteoporotic Vertebral Compression Fracture

Background:Percutaneous vertebroplasty with polymethylmethacrylate bone cement in the treatment of osteoporotic vertebra compression fractures is effective and rapid in pain relief. Objective:To evaluate the effectiveness of unipedicular percutaneous vertebroplasty with polymethylmethacrylate bone cement in the treatment of osteoporotic vertebral compression fractures.Methods:53cases of fresh osteoporotic vertebra compression fractures were performed unipedicular percutaneous vertebroplasty with polymethylmethacrylate bone cement. Their clinical data were analyzed retrospectively.Results:The follow-up time for the53cases was6months.①Of all the cases, Visual Analogue Scale scores since72hours (3.02±0.83vs6.89±1.41;P<0.001) and6months postoperation (1.32±0.471vs6.89±1.41;P<0.001)were significantly improved than those preoperatively;②The heights of anterior [(24.3±1.42) mm vs (15.49±1.96)mm; P<0.001] and intermediate vertebral body [(25.87±1.48) mm vs (17.49±1.88) mm; P<0.001] since72hours were significantly improved than those preoperatively; The heights of anterior [(23.15±1.44)mm vs (15.49±1.96)mm; P<0.001]and intermediate vertebral body [(24.58±1.08) mm vs (17.49±1.88) mm; P<0.001]6months postoperation were significantly improved than those preoperatively;③The angle of Cobb since72hours[(12.98±1.47)°vs (24.85±2.47)°; P<0.001] and6months[(11.87±1.48)°vs (24.85±2.47); P<0.001] postoperation were significantly improved than those preoperatively.④Poperties correlation analysis between the insertion amount of bone cement and Visual Analogue Scale scores since72hours(r=-0.18;P=0.900)and6months postoperation (r=-0.134; P=0.337);The heights of anterior vertebral body since72hours (r=0.25;P=0.875)and6months postoperation (r=0.089;P=0.525); The heights of intermediate vertebral body since72hours (r=0.047;P=0.740)and6months postoperation(r=0.043;P=0.740), and the angle of Cobb since72hours (r=-0.003;P=0.986) and6months postoperation(r=0.026;P=0.857)all suggests that r<0.3and P<0.05, therefore, there was no correlation between the insertion amount of bone cement and them.Conclusions:These findings suggest that unipedicular percutaneous vertebroplasty is effective in pain relief, however, the amount of bone cement has no influence on clinical effect including pain relief.