The Utility Of Functional Ultrasonic Imaging Technology In Acute Renal Allograft Rejection

【Object】 Base on the pre-research production，this study aimed to assess theclinical value of the Doppler ultrasound， three-dimensional ultrasound andcontrast-enhanced ultrasound. We acquired the most valuable parameters of the threeindividual technologies, and determined the critical point of the parameters above.Then we compared the efficiency of diagnosis of the three technologies. Also, Wecompared the change of the parameters before and after treatment.【Methods】1. One hundred and twenty patients were rolled in. They all underwentDoppler ultrasound，three-dimensional ultrasound and contrast-enhanced ultrasound.By drawing ROC curve, we acquired the most valuable parameters and their criticalpoint of the parameters. By comparing the area under the curve, we knew theefficiency of diagnosis of each technologies.2.Fifteen patients underwent Dopplerultrasound，three-dimensional ultrasound and contrast-enhanced ultrasound before andafter treatment, then we observe the change of the three technologies’ parameters.【Result】1.The comparison of Doppler ultrasound between the group of AR andstable renal function：the grade of color Doppler flow image （CDFI）was nosignificant difference（P＞0.05）；RI、PI were significant difference（P＜0.05）；the area under the curve was no significant differenc（eP＞0.05）.2. The comparison ofthe three-dimensional ultrasound between the group of AR and stable renal function：the grade of color Doppler energy image （CDEI）was no significant difference（P＞0.05）；MG、VI were no significant difference（P＞0.05）；VFI、FI、V weresignificant difference（P＜0.05）；the area under the curve of VFI、FI were bigger thanof MG、VI、V（P＜0.05）.3. The comparison of three-dimensional ultrasound betweenthe group of AR and stable renal function：the grade of color Doppler energy image（CDEI）was no significant difference（P＞0.05）；MG、VI were no significant difference（P＞0.05）；VFI、FI、V were significant difference（P＜0.05）；the areaunder the curve of VFI、FI were bigger than of MG、VI、V（P＜0.05）.4. Thecomparison of contrast-enhanced ultrasound between the group of AR and stable renalfunction： AT、TTP、mTT、QOF in the cortex and in medulla were no significantdifference（P＞0.05）；RT in the cortex and in medulla were significant difference（P＜0.05）；the area under the curve of RT in the cortex were bigger than of the otherparameters（P＜0.05）.5. The efficiency of diagnosis of the contrast-enhancedultrasound is higher than the other two technologies (P＜0.05).6. The comparisonof the three-dimensional ultrasound and contrast-enhanced ultrasound between thegroup before and after treatment: VFI、FI、V、RT in the cortex and in medulla weresignificant difference（P＜0.05）；【Conclusion】1.The efficiency of diagnosis of the contrast-enhanced ultrasound washigher than the other technologies. The most valuable parameters was RT in thecortex，the critical point of it was6.16s，with sensitivity of88.9%，specificity of64.4%.2. The efficiency of diagnosis of the three-dimensional ultrasound washigher than the Doppler ultrasound. The most valuable parameters were VFI andFI, the critical point of VFI was21.48%，with sensitivity of82.8%，specificity of67.7%，and the critical point of FI was48.46%，with sensitivity of82.8%，specificityof64.5%.3.There was no different parameter in the two pathological features ofacute rejection.4.The rate of change of RT in the cortex、VFI、FI、V before andafter treatment were different. RT in the cortex may prompt the recovery of renalfunction in the post-operation follow-up.