The Identification Value Of¹⁸F-FDG PET/CT In Digestive Tract Malignant Tumor With Lung Metastases And Multiple Primary Cancer

Objective In order to investigate the identification value of18F-FDG PET/CT in the digestivetract malignant tumor with pulmonary nodule between lung metastases,multiple primary cancer andbenign nodule.Materials and Methods Retrospective analysis was used for74cases of digestivetract malignant tumor patients with pulmonary nodules with18F-FDG PET/CT imaging esults. ThePET/CT results were compared with pathological findings and clinical follow-up results,andevaluating the differential value of18F-FDG PET/CT imaging in the diagnosis of digestive tractmalignant tumor with pulmonary nodule lesions. SPSS19.0software was used to statistical analysis,distribution differences of many groups cases compared by chi-square test, SUVmax, diameter(measurement) between group compared with rank-and-inspection, SUVmax, diameter (count)between group compared with the chi-square test; relation between SUVmax and focal diametersize using the Spearman rank correlation analysis and linear trend analysis. General comparisonbetween P <0.05for the difference was statistically significant, comparing two groups P <0.01forthe difference was statistically significant. Results In the74cases of digestive tract malignanttumor with pulmonary nodule lesions,32cases were lung metastatic tumors,11cases were lungprimary cancer and31cases were lung benign nodules; Multiple nodules57cases, isolated tubercle17cases; Double unilateral lung nodule distribution difference is not statistically significant (P>0.05), the main pulmonary nodule distribution of difference was statistically significant (chi-square=16.399, P=16.399), the largest diameter difference between three groups was statisticallysignificant (chi-square=22.518, P <0.0001), SUVmax difference between three groups wasstatistically significant (chi-square=30.080, P <0.0001), SUVmax and lesion size was positivelyrelated to the diameter (r=0.809, P <0.0001), the difference between different edge features inthree groups was statistically significant (chi-square=18.529, P <0.0001). This study18F-FDGPET/CT for lung nodules in qualitative diagnosis of sensitivity, specificity, accuracy, positive predictive value and negative predictive value were50.00%,93.33%,81.08%,71.43%,81.08%;SUVmax acuity2.5as malignant diagnosis threshold value in the diagnosis of pulmonary nodulesof sensitivity, specificity, accuracy, positive predictive value and negative predictive value were81.40%(35/43),80.65%(25/31),81.08%(60/74),85.37%(35/41),75.76%(25/33). ConclusionsIn18F-FDG PET/CT imaging diagnosis and differential diagnosis of digestive tract malignant tumorwith pulmonary nodules in the clinical application of the oven, in addition to doubt the possibilityof metastases, we also should pay attention to the possibility of multiple primary cancer. Analysisof lung nodules is of great value to the degree of metabolism of the oven, SUVmax positivelycorrelated with the size of the pulmonary nodules, the size of the primary lung cancer and lungmetastases of18F-FDG uptake were significantly higher than those in lung benign nodules, andmetastases to the lungs and pulmonary18F-FDG uptake between primary lung cancer has noobvious difference,but SUVmax cannot serve as the only diagnostic basis, at the same time shouldalso be combined with the history, laboratory examination, especially analyzing the morphologicalfeatures of CT image.