Prevalence And Risk Factors Of Abnormal Left Ventricular Geometrical Patterns In Hypertensive Patients

BackgroundThe patterns of left ventricular geometry may predict cardiovascular events, but not much data are available in Chinese. We investigated the prevalence of different patterns of left ventricular geometry and their risk factors in hypertension population in northern China.MethodsA total of2811patients with hypertension were recruited from two Chinese communities. Left ventricular hypertrophy was defined by using the criteria of the left ventricular mass index (LVMI) more than115g/m2for men and95g/m2for women, respectively. The left ventricular geometry was classified into four patterns:normal; abnormal, defined as concentric remodeling; concentric or eccentric hypertrophy based on the values of LVMI and relative wall thickness. Logistic regression model was applied to determine the odds ratio (OR) and95%confidence intervals (CI) of the risk factors of left ventricular hypertrophy.ResultsThe prevalence of left ventricular hypertrophy was26.0%(n=732) in patients with hypertension (n=2811), much higher in women (39.3%,n=492) than in men (15.4%(n=240)(PO<0.01). The prevalence of LV geometrical patterns was37.0%,15.7%,10.4%for concentric remodeling, concentric and eccentric hypertrophy, respectively. After adjustment by using Logistic regression model, the risk factors for left ventricular hypertrophy were female (OR2.555,95%CI2.015-3.240, P<0.01), age (OR1.043,95%CI1.033-1.053. P<0.01), systolic blood pressure (OR1.020,95%CI1.015-1.026, P<0.01), body mass index (OR1.091,95%CI1.061-1.122. P<0.01), hypertensive medication history(OR1.915,95%CI1.567-2.340, P <0.05), smoking history (OR1.315,95%CI1.006-1.720, P<0.01). Drinking history showed a protective factor for left ventricular hypertrophy (OR0.657,95%CI0.490-0.882, P<0.01). The risk factors for abnormal left ventricular geometry were age. sex. systolic blood pressure, and body mass index, duration of hypertension, hypertensive medication history. And also drinking history showed a protective factor. ConclusionsThe echocardiographic left ventricular hypertrophy and left ventricular geometric abnormality were much prevalent in hypertensive population in northern China. Echocardiography patterns of left ventricular geometry may be used to guide treatment of hypertension-related heart damage.