The Correlation Study Between The Atherosclerosis Of Femoral Arteries, Abdominal Aorta, Carotid Arteries And Coronary Atherosclerosis Detected By Ultrasound

Objective: We used two-dimensional high frequency ultrasound to detect theintima-media thickness (IMT) and the plaques formation of femoral arteries, abdominalaorta and carotid arteries of the patients who took coronary arteriography1week later.Then we discussed the correlation between the atherosclerosis of femoral arteries,abdominal aorta, carotid arteries and coronary atherosclerosis, and evaluated thepredicting value and its clinical meaning of the atherosclerosis of femoral arteries,abdominal aorta and carotid arteries to coronary atherosclerosis.Methods: We used high frequency ultrasound to measure the intima-mediathickness, plaques scores and the numbers of patches of femoral arteries, abdominalaorta and carotid arteries of109patients who hospitalized in the heart internal medicinedepartment of our hospital and took coronary angiography1week later. According tothe stenosis results of coronary angiography, all the patients were divided into threegroups. Respectively,39cases of coronary artery without stenosis or stenosis rate <50%were enrolled as the normal control group, including22males and17females; thepatients of coronary artery stenosis rate≥50%were enrolled as the experimental group.The experimental group was divided into two groups according to the different numbersof stenosis branches of coronary artery. There were34cases in the single stenosisbranch group, including23males and11females. There were36cases in the multiplestenosis branches group (including double stenosis branches), including26males and10females. We used the intima-media thickness (IMT), atherosclerotic plaquesthickness and plaques numbers as the observation index, and collected the basicinformation and blood lipids biochemical findings of patients simultaneously.Results:1. There was the statistical significance (P<0.05) in age, gender, BMI,smoking index, systolic blood pressure, diastolic blood pressure, fasting blood glucose (BS), triglyceride (TG) between the normal control group and the experimental group ofcoronary artery. They were the risk factor for atherosclerosis. There was no statisticalsignificance (P>0.05) in cholesterol (TC), high density lipoprotein (HDL-ch), lowdensity lipoprotein (LDL-ch) between the normal control group and the experimentalgroup of coronary artery.2. The results showed the positive correlation in the intima-media thickness (IMT),plaques scores, the numbers of plaques of femoral arteries, abdominal aorta, carotidarteries between the single stenosis branch group with coronary angiography and thenormal control group (P<0.05),the multiple stenosis branches group with coronaryangiography and he normal control group(P<0.01),the single stenosis branch group andthe multiple stenosis branches group(P<0.05).The involved branches of coronary arteryincreased with the increasement of the IMT, the plaques scores, and the numbers ofplaques of femoral arteries, abdominal aorta and carotid arteries. The value of themultiple stenosis branches group of coronary artery was maximum.3. The formation results of plaques of femoral arteries, abdominal aorta andcarotid arteries to the prediction of coronary atherosclerosis: The sensitivity, specificity,accuracy, positive predictive value and negative predictive value of femoral arteriesplaques predicting coronary atherosclerosis was89%,77%,84%,88%,79%respectively. The sensitivity, specificity, accuracy, positive predictive value andnegative predictive value of abdominal aortic plaques predicting coronaryatherosclerosis was73%,72%,72%,82%,60%respectively. The sensitivity, specificity,accuracy, positive predictive value and negative predictive value of carotid arteriesplaques predicting coronary atherosclerosis was83%,79%,82%,87%,72%respectively. The sensitivity and accuracy of femoral arteries plaques had the positivecorrelation with abdominal aortic plaques (P<0.05). The femoral arteries, abdominalaorta and carotid arteries had the good predictive value on coronary atherosclerosis.4. Femoral arteries, abdominal aorta and carotid atherosclerosis to the predictiveeffect of coronary atherosclerosis: with multivariate Logistic regression analysis, itshowed the atherosclerosis of femoral arteries, abdominal aorta and carotid artery hadthe positive correlation with coronary atherosclerosis (P<0.01, P<0.05). The correlationof the atherosclerosis between abdominal aortic, carotid arteries and coronary artery wasinferior to femoral arteries.Conclusions: Age,gender, systolic blood pressure and diastolic blood pressure,fasting blood sugar (BS), triglycerides (TG), smoking, body mass index were the atherosclerosis risk factors;The intima-media thickness (IMT) and the formation ofplaques of femoral arteries, abdominal aorta and carotid arteries can indirectly predictthe different degrees of coronary atherosclerosis, and the sensitivity and accuracy offemoral arteries are better than abdominal aorta.