Epidemiological Characteristics Of Obesity And Relationship Of Anthropometric Indexes And Stroke Among Anqing Rural Areas Population

Objective: Obesity is closely related to stroke, and obesity is divided into differenttypes according to different criteria, different indexes of obesity and the associations ofstroke are controversy. The study examined the epidemiological characteristics ofoverweight and obesity among the population in Anqing rural areas, discuss therelationship of stroke and subtypes with anthropometric indexes, including body massindex (BMI), waist circumference (WC), waist-to-hip ratio (WHR) and waist-to-heightratio (WHtR). To control the progress of the rural population obesity prevalence, andfurther provide a scientific basis for prevention and control the occurrence of stroke. Atthe same time, this study accumulated a large sample of data for epidemiologicalcharacters of rural population in China. Method The58530participants who wereenrolled from1995to2005at baseline studies in Anqing and the surroundingcommunities were investigated, including bronchial asthma, osteoporosis, high bloodpressure, twin, dietary nutrition research and so on, and followed up the participantsfrom2010to2011. Cox’s proportional hazard model was used to investigate theassociation between the four obesity indexes and stroke. BMI≥24was divided asoverweight and BMI≥28for obesity’s cutoff point. WC≥85cm in males, WC≥80infemales, WHR≥0.9in males, WHR≥0.85in females or WHtR≥0.5as the boundariesabdominal obesity Results:18950participants were selected into the analysis. During amedian of6.3years follow-up,371participants developed stroke events. The proportionof overweight and obesity in men were13.40%and2.06%, respectively. Amongwomen, the corresponding proportions were20.83%and3.79%. The proportion of WC ≥85in men and WC≥80cm were14.38%and26.60%; WHR≥0.90in men andWHR≥0.85in women were20.41%and33.84%; WHtR≥0.5were20.72%in men and37.50%in women. Individuals were divided into three15-year groups, BMI was at thehighest levels in30~45years old group in men and women; WC was at the highestlevel in30~45years old group in men, and45~60years old group in women; WHRand WHtR were in the≥60years old group in both men and women. In the obesitygroup(BMI≥28),the proportions of men with WC≥85cm,or WHR≥0.9,or WHtR were96.68%、90.05%and98.10%，among women the corresponding proportions were97.88%、81.82%and98.79%. After adjustment for age, smoking and drinking alcohol,women with BMI>=24kg/m2could increase the risk of total stroke, the HR value was1.48(95%CI,1.03-2.13). Additional adjusted for systolic pressure and diastolic pressuresubstantially attenuated the hazard ratios, HR values was0.97(95%CI,0.67-1.40). Andin men, the relation between BMI and total stroke and subtypes were no statisticallysignificant. After adjustment for age, smoking and drinking alcohol, men withWHR≥0.9and WC≥85cm could significantly increase the risk of total and ischemicstroke, and men with WHtR≥0.5could statistically associated with stroke and subtypes.And in women, WC could significantly increase the risk of total and ischemic stroke;WHR and WHtR were the risk factors to total stroke, and WHR also could increase therisk of hemorrhagic stroke. Additional adjusted for systolic pressure and diastolicpressure substantially attenuated the hazard ratios, and only in men we could findWC≥85cm and WHR≥0.9could Significantly increased by89%and83%of the risk forischemic stroke, the HRs values were1.89(95%CI,1.04-3.41) and1.83(95%CI,1.09-3.07). Conclusion:(1) The overweight and obesity rates of Anqingand surrounding communities were relatively low, but abdominal obesity prevalencewas high, and women more than men, have the features of general obesity combinedabdominal obesity;(2) The mean values of BMI and WC of Anqing and surroundingcommunity people, no matter male or female all higher in young people, WHR and WHtR were higher in old people. Therefore, the health propaganda and education ofobesity should promote in all ages, control obesity regardless of age, early preventionand control, to further prevent cardiovascular disease;(3) The obesity indexes canincrease the risk of stroke, although the relationships were highly modified by systolicpressure and diastolic pressure in certain degree., but still show that no matter generalobesity or abdominal obesity are risk factors for stroke and its subtypes. Warningpeople in daily life can through these simple noninvasive measuring operations ofself-monitoring, reasonable diet, movement actively, by controlling the body weight toprevent the risk of stroke.