The Significance Of Detecting NE, Citric Acid And PH Of EPS In The Diagnosis Of Type â…¢ Prostatitis

ObjectiveTo explore the significance of detecting the NE, citric acid and pH in the diagnosis of type Ⅲ prostatitis.MethodsDid bacterial culture, routine examination of EPS and evaluated the NIH-CPSI score of the65patients diagnosed as type Ⅲ A prostatitis,116patients diagnosed as type Ⅲ B prostatitis and116people as controlled group. Detected the NE concentration, citric acid concentration and pH level. The data was analyzed by independent samples t-test between each two groups. Did the Spearman correlation analysis between each indicators of experimental group. Analyzed the level of NE, citric acid and pH between two experimental groups, experimental group and control group respectively with the ROC curve, evaluating the significance of NE, citric acid and pH in the diagnosis of type Ⅲ prostatitis.Results〤omparison between ⅢA and controlled group:There were significant differences in NIH-CPSI score, leucocyte count, the level of NE, citric acid and pH. There were strong correlation between NE concentration, pH level, citric acid concentration and leucocyte count (NE:r=0.806, p<0.05; pH:r=0.782, p<0.05; citric acid; r=-0.803, p<0.05). While the correlation between CPSI score and leucocyte count was not statistically significant.②Comparison between IIIB and controlled group:The NIH-CPSI score, NE concentration, citric acid concentration and pH level between these two groups was significantly different. The leucocyte count didn’t reach a statistical difference.③Comparison between experimental groups (ⅢA+ⅢB) and controlled group: The NIH-CPSI score, leucocyte count, NE concentration, citric acid concentration and pH between these groups were significantly different. The correlation between NE concentration, pH level, citric acid concentration and leucocyte count (NE:r=0.939, p<0.05; pH:r=0.840, p<0.05; citric acid:r=-0.910, p<0.05) reached statistical difference. While the correlation between CPSI score and leucocyte count was not statistically different. Other strong correlation found in the experimental was NE concentration with citric acid concentration(r=-0.872, p<0.05)、NE concentration and pH level(r=0.808, p<0.05), citric acid concentration and pH level (r=-0.825, p<0.05). The ROCAUC of NE concentration, citric acid concentration, pH level between experimental groups was0.991,0.978and0.944respectively, which was statistically different. The ROCAuc of CPPSI was0.492, which didn’t reach statistical difference. The ROCAUC of NE concentration, citric acid concentration, pH level, leucocyte count between experimental groups and controlled group was0.811,0.978,0.881,0.726respectively, which was statistically different.ConclusionDetecting the NE concentration, citric acid concentration and pH level of EPS plays an important role in the diagnosis of type Ⅲ prostatitis, which could show the severity of the disease in some degree. The ROC curve analysis indicates that the NE concentration, citric acid concentration and pH level of EPS are valuable indicators in the diagnosis of type Ⅲ A prostatitis and type ⅢB prostatitis.