| Objective: Using randomized, controlled study, clinical observation of themyocardial kang scheme electrocardiogram (ecg) in patients with acute phase of viralmyocarditis and the influence of dynamic electrocardiogram (ecg), myocardial damagemarkers, the evaluation of myocardial kang scheme to treat acute viral myocarditiscurative effect, thus for the formation of viral myocarditis, standardize the diagnosisand treatment of acute stage system solutions to provide clinical basis.Methods:sity of TCM affiliated longhua hospital inpatient and outpatient patients157cases, all cases are in line with the1998national myocarditis cardiomyopathyworkshop of adult acute viral myocarditis diagnostic reference standard. Throughmultiple centers were randomly divided into control group and experimental group.Control group76cases,81cases of experimental group. Two groups of cases all havedifferent degrees of heart palpitations, chest tightness and other symptoms. Controlgroup given conventional western medicine treatment, coenzyme Q10slice10mgorally,3times/day, vitamin C piece of0.2g,3times/day of oral, course of treatmentfor30days; Experimental group according to the result of syndrome differentiation oftraditional Chinese medicine give corresponding myocardial solution treatment,Chinese medicine treatment for30days; Foundation treatment at the same time givetwo groups: limit activity and rest adequately, easy to digest, is rich in vitamin, proteindiet, intravenous application of polarized liquid (15ml500ml+10%potassiumchloride10%glucose plus insulin8u), inosine (400mg), once per day, treatmentcourse2weeks. Observe patients’ ecg (including conventional and dynamic ecg),myocardial enzymology.iResults:(1) Clinical analysis of ECG of two groups before treatment， twogroups of patients with ECG ST segment changes，41cases of experimental group，32 cases in the control group， after treatment the test group was82.50%，control group59.38%， compared with two groups of ST segment of ECG curative effect，the testgroup than in control group (P <0.05).(2) Analysis of two groups of dynamic ECG，dynamic ECG normal rate beforetreatment， the test group was9.10%，9.59%in the control group， the two groups hadno statistical significance (P>0.05)，59.72%for the experimental group aftertreatment，51.56%of the control group，the two groups had no statistical significance(P>0.05)，as compared with that before treatment within the group，the two groupshad statistical significance (P<0.05)， showed that two groups can improveelectrocardiogram， no difference between the two groups.(3) Through the observation of the number of premature beat, numerical comparisonbefore and after treatment with no statistical significance (P>0.05), the results showthat failed to reduce the number of premature beat, majority of thought is associatedwith less sample size.(4) Myocardial injury markers curative effect analysis, in the two groups before andafter treatment of myocardial damage markers (troponin I and CK-MB), creatinekinase isozyme comparison, there were no statistical significance (P>0.05), in theacute phase of viral myocarditis, myocardial cell damage, biochemical examinationcan have higher markers of myocardial injury, the increased myocardial markers:usually they last about7to14days can recover, this may be associated with viralmyocarditis disease itself characteristic, because this study looked at a short course ofdisease (30days), most of the patients with myocardial enzyme had returned tonormal.(5) Comprehensive efficacy total effective rate in both groups, experimental group15cases cured,30cases were markedly improved,28cases, effective and invalid6cases,total effective rate92.41%; Control group cure9cases,15cases were markedlyeffective, effective32cases,13cases, total effective rate81.16%, two groups ofintegrated total effective rate and level of curative effect comparison, comprehensivecurative effect is better than that of control group, experimental group the differencewas statistically significant (P <0.05).Conclusion:(1)Clinical studies show that myocardial Kang scheme cansignificantly improve the adult acute viral myocarditis ECG and dynamic ECGpathological changes.(2) Study on premature beats， because of the small sample size， each index and the control group had no statistical significance.(3) Myocardial injury markers for myocardial Kang adult acute viral myocarditisintervention， due to the characteristics of the observation time and the disease itself，the two groups had no statistical significance analysis， further research.(4) Xinjikang scheme is better than that of adult acute viral myocarditis ofexperimental group comprehensive treatment control group. |
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