Research Advances In The Exhaled Breath Condensate Detection For OSAHS

The pathophysiology of obstructive sleep apnea hypopneasyndrome(OSAHS) is mainly related to airway inflammation andoxidative stress. The exhaled breath condensate(EBC) detection, as anew way of non-invasive studying pulmonary diseases which reflectairway inflammation,oxidative stress and acid-bases，has advantages ofbeing easily carrying out，real-time monitoring，repeatability andbetter patients acceptance. Collecting some biomarkers in EBC forOSAHS,which could assist in the diagnosis of OSAHS,the severityof this disease，and the evaluation of treatment. Identification of abno-rmal markers in EBC may provide new opinion on the pathogenesisof OSAS and new therapeutic.In this review we will inquiry literatures about obstructive sleep apnea hypopnea syndrome、exhaled breathcondensate、biomarkers from some databases,analyse and summarizethese literatures.Finally we discuss the exhaled breath condensate detection,the feature and significance of some biomarkers in EBC of patients with OSAHS,its problems and prospects of this technique.