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The Advantage Of Using Optical Coherence Tomography Evaluate For Chinese Herbal Medicine In Treatment Central Exudative Chorioretinopathy

Posted on:2015-01-18Degree:MasterType:Thesis
Country:ChinaCandidate:Y GaoFull Text:PDF
GTID:2254330428981533Subject:Medicine facial scientific
Abstract/Summary:PDF Full Text Request
Objective1.Discuss advantages of optical coherence tomography (OCT) technology as evaluation standard of central exudative chorioretinopathy (CEC) curative effect.2.Evaluate treatment effect of traditional Chinese medicine on CEC.Methods CEC patients for routine eye examination, Amsler form examination, vision examination, fundus fluorescein angiography (fundus fluorescsin angiography, FFA) examination and OCT examination, according to inclusion and exclusion criteria were selected to meet the requirements of the40cases,43eyes were randomly divided for the treatment group and control group, treatment related. Heat treatment group into the network-based oral evil CEC patient self-made medicine, a daily,2times a decoction. The control group was treated with prednisone tablets (Prednisolone acetate),2pills one time,3times a day, pancreatic kallikrein enteric-coated tablets (Yee opening film,60mg/tablets),2pills one time,2times a day. In a month for a course of treatment three courses. OCT conducted every month review, the morphological changes observed before and after treatment of macular tomographic image, change the height of macular edema, macular retinal thickness and choroidal neovascularization (choroidal neovascularization, CNV) composite thickness. After3months after treatment to routine eye examination, Amsler form inspection, vision inspection, FFA, OCT examination. And statistical analysis.Results1.OCT some small macular lesions such as mild macular edema, hemorrhage, or observe the occult CNV, diagnosis relative to the FFA has obvious advantages.2. treatment group20cases23eyes, the total effective rate was64.2%in the control group20cases21eyes, the total effective rate was15.4%. Two groups of patients before and after treatment visual acuity, field of vision30e significantly improved light sensitivity, Amsler sheet improved significantly distort the missing degrees, retinal hemorrhage, edema, exudation observed indicators have improved, the efficacy of the treatment group than the control group (P<0.05). Conclusion1. OCT images clearly show the structure of the retina at all levels, and the structure of the retina various qualitative and quantitative analysis, the relative advantage of other checks. CEC heat evil into the network type pathogenesis of anger flaming, upside the head, or liver qi stagnation, Yu gang, hot camp blood, burns fundus Sun network, forcing the extravasation of blood and bleeding, CEC activities and convalescent to heat syndrome, empirical common, CEC activities of OCT is displayed on the large amount of bleeding, oozing more, edema, weight, accompanied by CNV, the most visible reflection layer (RPE/CC) fracture, fracture zones in a multi-, reflecting the strong uplift retina (red light zone), recovery visible reflection of stronger activity than the performance of a complex mixed with various densities strong reflection area surrounding the lesion reflection smooth, connected with the strong reflex zones corresponding RPE lesion center still showed a strong red reflex. OCT examination results thus favor the disease early detection, early treatment, the Chinese dialectical therapy CEC’s important diagnosis.2Chinese medicine treatment CEC has a significant effect. By CEC syndrome type for treatment, so that patients improve or stabilize visual acuity, visual field mean sensitivity increased, retinal bleeding and oozing partially or completely absorbed. CNV can be reduced.
Keywords/Search Tags:optical coherence tomography, central exudative chorioretinopathy, syndrome of Heat invading collaterals, Traditional Chinese medicine
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