| Objective:Through retrospective investigation analysis and summary of related factorsaffecting the pregnancy outcome of recurrent spontaneous abortion,put forward themeasures of prevention and cure of reasonable and effective guidelines for clinical.Methods:Through the collection of the First Affiliated Hospital of Anhui University oftraditional Chinese medicine in2011January to2013January gynecology ward andoutpatient130cases of the patients with recurrent spontaneous abortion diagnosis.Throughfollow-up of patients with pregnancy outcome,130patients were divided into thesuccessful group (the final live birth patients) and the failure group (that eventuallyfailed to live birth patients).By two independent samples t test, χ2test of single factoranalysis and dichotomy Logistic regression analysis to the two groups of patient’sage,when see a doctor have abortion symptom or no,regulate situation,menstruationsituation,the number of abortion,the number of spontaneous abortion, gestational weeksin treatment,the time of fetus protection,syndrome of TCM,western medicine etiology,obtainthe related factors that affect the outcome of pregnancy.Results:1. Pregnancy outcome statistics:the follow-up statistics obtained the successful groupswith a total of99cases,accounted for76.15%,the failure group with a total of31cases,account for23.85%.2. The outcome of pregnancy and age distribution:the successful group of at least20years of age,themaximum of41years old,the average ageis30.42±4.352years old,concentrationdistribution in the age of25to34years old;the failure group of at least22years ofage,the maximum of42years old,the average age is32.32±5.21years old,concentrationdistribution in the age of30to34years old.3. Pregnancy outcome with the symptoms of abortion clinic situation:the successful group have abortion symptoms were73cases, account for73.74%of successful group,no abortion symptoms were26cases,account for26.26%;the failure group have abortionsymptoms were23cases,account for the failure group74.19%, no abortion symptomswere8cases, account for25.81%.4. Pregnancy outcome with regulate situation: the successful group80cases haveregulate(progestation regulate or without abortion symptoms began fetus protectionafter pregnancy), account for80.81%of successful group,19cases without regulate(progestationwithout regulate and have abortion symptoms began fetus protection after pregnancy),accountfor19.19%; the failure group7cases have regulate, account for the failure group22.58%,24cases without regulate,account for77.42%.5. Pregnancy outcome with menstruation situation:the successful group of menstrualdisorders were29cases,70cases were eumenorrhea;the failure group of menstrualdisorders were16cases,15cases were eumenorrhea.6. Pregnancy outcome with the number of abortion and spontaneous abortionsituation:the successful group abortion is at least2times, up to6times, the average numberof abortion is2.79±1.11times,the failure group abortion is at least2times, up to8times,the average number of abortion is3.68±1.51times;the successful group spontaneousabortion is at least2times, up to6times, the average number of times of spontaneousabortion is2.44±0.80times,the failure group spontaneous abortion is at least2times,up to7times, the average number of times of spontaneous abortion is2.90±1.22times.7. Pregnancy outcome with gestational weeks in treatment distribute situation:thesuccessful group gestational weeks in treatment minimum is3weeks, the maximum is13weeks, the average gestational weeks is5.45±1.67weeks;the failure group gestationalweeks in treatment minimum is4weeks, the maximum is9weeks, the average gestationalweeks is6.26±1.44weeks.8. Pregnancy outcome with fetus protection time situation:the successful group offetus protection over previous abortion time of patients with a total of89cases, accountfor the successful group89.90%,not exceed previous abortion time of patients with a total of10cases,account for10.10%;the pregnancy failure group over previous abortiontime of patients with a total of12cases, account for38.71%of the failure group, notexceed previous abortion time of patients with a total of19cases, account for61.29%.9. Pregnancy outcome with syndrome of TCM distribute situation:kidney deficiencysyndrome is most common in the syndrome of TCM distribution of the success groupand the failed group,then is spleen kidney deficiency syndrome,kidney deficiency andblood stasis syndrome.10. Pregnancy outcome with western medicine etiology:the successful group of unknownetiology accounted for44.44%,have clear etiology in patients the most common factors isimmune factors,endocrine factors and reproductive tract infection factors,the proportionrespectively30.3%,18.18%,11.11%;unknown reasons accounted for48.39%of the failedgroup,common cause is immune factors,endocrine factors and reproductive tract infectionfactors,theproportionrespectively29.03%,16.13%,12.9%.11. The two independent samples t test,χ2test were used for univariate analysis of twogroups of patients with age,regulate situation, menstruation situation,the number ofabortion,thenumber ofspontaneous abortion,thetime of fetus protection havedifferences arestatistically significant(P<0.05),finally, the dichotomy of Logistic regression analysis resultshowed that the number of spontaneous abortion, regulate situation,the time of fetusprotection are the factors influencing the outcome of pregnancy.Conclusion:1. Spontaneous abortion times have influence on the pregnancy outcome in the patientswith recurrent spontaneous abortion,with the increase of the number of spontaneousabortion will reduce pregnancy success rate.2. Regulate before pregnancy and early fetus protection after pregnancy the pre cultivates theloss can improve the success rate of pregnancy of patients with recurrent spontaneousabortion.3.The time of fetus protection have influence on the pregnancy outcome in patients with recurrent spontaneous abortion,pregnancy after full course of fetus protection meanmore than previous abortion time can improve the patients with recurrent spontaneousabortion of pregnancy success rate.4. Kidney deficiency syndrome is most common in the syndrome of TCM distribution inpatients with recurrent spontaneous abortion,then is spleen kidney deficiency syndrome,Kidneydeficiency and blood stasis syndrome.5.Common western medicine etiology of patients with recurrent spontaneous abortionwere immune factors, endocrine factors and reproductive tract infection factors... |
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