Xinshuaining Mixture In Treating Coronary Heart Disease Ischemic Cardiomyopathy Type Of Heart Failure (heart Deficiency) Clinical Efficacy

Objective:to observe the treatment of coronary heart disease (CHD) heart better mixture ischemic cardiomyopathy type heart failure (heart kidney Yang deficiency) type of patients with clinical curative effect.Methods:The60cases of syndrome differentiation of traditional Chinese medicine for coronary heart disease, ischemic cardiomyopathy patients with heart failure (heart kidney Yang deficiency)type, randomly divided into treatment group (30cases) and control group(30cases), control group using conventional western medicine therapy (aspirin and simvastalin, enalapril and tartaric acid metoprolol, drug combination, continues to have heart failure symptoms can add land by integrating), The treatment group in the control group on the basis of better mixture, add with heart failure, a course of1months, observe two groups after treatment in patients with New York heart association (NYHA)cardiac function classification effect, TCM syndrome hou curative effect, the plasma NT-ProBNP level index, heart colour to exceed, noninvasive cardiac detection, And record the adverse reaction, so as to assess the efficacy, tolerability and safety.Results:rative effect, heart function NYHA classification, plasma NT-ProBNP level,left ventricular ejection fraction(LVEF), noninvasive cardiac function examination, level index of treatment group is better than the control group, Significant difference (P<0.05);can effectively improve the clinical symptoms and signs treatment group (P<0.05), heart exceeds the results (P<0.05), Increase ejection fraction,can significantly reduce the plasma NT-ProBNP level (P<0.05), treatment group total effective rate was96.7%, the control group total effective rate was86.6%. Treatment group is better than the control group(P<0.05). Two groups of patients before age, sex, treatment of TCM symptoms score and treatment before cardiac function classification data such as there was no significant differences. In before and after treatment respectively, urine, blood, liver and kidney function check all did not found significant change.Conclusion:1. Heart failure is better than a mixture combined with regular western medicine treatment of coronary heart disease, ischemic cardiomyopathy patients with heart failure (heart kidney Yang deficiency) type, To further improve the clinical curative effect of pure western medicine treatment, Can alleviate coronary ischemic cardiomyopathy heart failure(heart kidney Yang deficiency) type the patient’s clinical symptoms, signs, Further improve heart function, Improve patients with left ventricular ejection fraction. And no toxic and side effects;2.Heart failure is better than a mixture combined with regular western medicine treatment of coronary heart disease, ischeroic cardiomyopathy patients with heart failure (heart kidney Yang deficiency)type can obviously decrease the plasmaT-ProBNP content;3. fully reflect the syndrome differentiation of traditional Chinese medicine, ForTCM syndrome differentiation and treatment of coronary heart disease, ischemic cardiomyopathy type heart failure (heart kidney Yang deficiency)model provides a theoretical basis, And laid a good foundation for further research.