Studies To Determine The Distribution And Drug Laws Based On Data Mining Unstable Angina Pectoris Syndrome

Objective:To explore the distribution of TCM syndrome elements of unstable angina, and medication rule.Methods:Through the Clinical-Research System, extract the related data, such as syndrome elements, TCM decorations from the medical records of325patients with unstable angina, conduct data mining analysis by using modern statistical methods.Results:1.The most common syndrome element is Blood stasis (69.54%),follow by Qi deficiency (61.23%), Phlegm (53.85%), Yin deficiency (41.85%), Heat (16.62%), Yang deficiency (13.85%), Qi stagnation (7.69%), Retained-fluid (5.54%), Blood deficiency (2.15%), Cold coagulation (1.23%), Wind-cold (0.31%). The most common element of disease location is heart (100%), follow by kidney (9.85%), spleen (8%), liver (6.77%), lung (3.38%), gallbladder (0.62%);2.The most common type of combination of syndrome according to the amount of syndrome elements is double-factor, follow by three-factor, four-factor, single-factor, five-factors, six-factors; According to the nature of the disease, the intermingled deficiency and excess type is the most, follow by excess type, deficiency type; Of all the combination of syndrome, Blood stasis+Yin deficiency+Qi deficiency+Phlegm is the most common, follow by Blood stasis+Yin deficiency+Qi deficiency, Blood stasis+Qi deficiency, blood stasis and, Qi deficiency and blood stasis and phlegm+phlegm;3. Syndrome element pairs whose support>10%,corr>1are Qi efficiency-Yin deficiency, Phlegm-Heat, Blood stasis-yin deficiency, Blood stasis-Qi deficiency, Blood stasis-phlegm, Qi deficiency-Phlegm, Phlegm-Yin deficiency.4.The number of herbs whose support>5%is70.The top five are Poria, Radix Astragali, Rhizoma Pinelliae,radix salvia,miltiorrhizae.5.14pairs of herbs whose support>5%, corr>1≥50%, confidencel and confidence2≥50%or confidencel>90%or confidence2≥90%are found. They are Oyster-Keel, Ginger-Jujube, Polyporus-Alisma orientale, Peach kernel-safflower, Salvia miltiorrhiza-sandalwood, Trichosanthes kirilowii-Allium macrostemon, Schisandra chinensis-Radix ophiopogonis,Red peony root-Peach kernel, Schisandra chinensis-Radix pseudostellariae,Ligusticum chuanxiong-Angelica,Pinellia tuber-Dried orange peel,Cassia twig-Snakegourd,Pinellia tuber-Snakegourd,Polyporus umbellatus-Poria.6.After visual processing of the herbs whose support>10%,corr>1in the syndrome elements whose frequency>10%,five core herb groups are found. They are Ligusticum chuanxiong-angelica-radix rehmanniae-radix paeoniae rubra-peach kernel- safflower,Schisandra-ginseng-Ophiopogon japonicus-radix salviae miltiorrhizae-Radix astragali,Dried tangerine peel-pinellia-Poria-licorice,Snakegourd-Allium macrostemon Bunge-cassia twig,Coptis-pinellia tuber-snakegourd.Conclusion:1.The top four syndrome elements of unstable angina pectoris of coronary heart disease in beijing are Qi deficiency, Yin deficiency, Phlegm, Bood stasis. They usually combine with each other;2The medical regularity sorted out by data mining objectively reflects the the thought of prescriptions of traditional Chinese medicine of Cardiology of Guanganmen Hospital in treating UA, that is, take tonifying Qi,Promoting blood circulation, eliminating phlegm, nourishing Yin as the main treatment method, assisted by regulating Qi, warming Yang, eliminating heat, and alleviate water retention and so on when in need.