| Objective:To study the components of the metabolic syndromes, study of risk factors associated syndromes and the lower extremity arterial intima-media thickened, hoping to get factors of lower extremity arterial intima-media thickened or not,the relationship with MS syndromes and lower limb arterial intima-media thickened, that can early predict Cardiovascular and cerebrovascular diseases, peripheral vascular disease and syndrome differentiation type of metabolic syndrome.Methods:Based on the research of the inclusion and exclusion criteria,108patients of metabolic syndrome were collected from2013January to2014Januaiy in Department of trrditional Chinese medicine of Beijing Hospital,according to 《national standard of the people’s Republic of China)) and our experience.the pationls of metabolic syndrome with four TCM syndromes of both qi and Yin deficiency, Yin deficiency and dryness-heat,phlegm wet resistance and phlegm blood stasis blocking collaterals. Collect the patient’s general condition and clinical data, statistical analysis of the general situation is different TCM syndrome type, the factors affecting the lower extremity arterial intima thickened or not.Results:1.The selected98cases of MS patients based on TCM syndrome types successively were Both Qi and Yin deficiency group (30.6%), Phlegm blood stasis blocking collaterals group (28.6%), phlegm wet resistance group (21.4%), Yin deficiency and dryness-heat (19.4%).2.5ages of The selected98cases of MS patients based on TCM syndrome types (<45years,45to59years,60to74years,75to89,>90years old) frequency distribution of3,28,37,30,0, where the ratio of60to74years group is the highest37.4%, the proportion of patients over60years up to67.7%.3. In the average age, Both Qi and Yin deficiency> Phlegm blood stasis blocking collaterals group> Yin deficiency and dryness-heat> phlegm wet resistance, no significant difference between the groups (P>0.05).4. Comparing the significant difference in BMI, Phlegm blood stasis blocking collaterals group> phlegm wet resistance group> Yin deficiency and dryness-heat> Both Qi and Yin deficiency group, Both Qi and Yin deficiency have two groups with various aspects of phlegm wet resistance and Phlegm blood stasis blocking collaterals (P<0.05), the rest of the group had no significant difference (P>0.05).5. Combined coronary heart disease, cerebrovascular disease, fatty liver was followed by the proportion was25.6%,24.5%,66.3%. there was no significant difference (P>0.05) in coronary heart disease, cerebrovascular disease and fatty liver in the presence or absence of TCM syndrome types. Phlegm blood stasis blocking collaterals combined coronary heart disease and cerebrovascular disease is maximum.6.98MS patients cases have100%of with diabetes, in terms of HbA1c, compared with Both Qi and Yin deficiency group Yin hot, phlegm wet resistance groups were significantly different (P<0.05). Three stages of diabetes duration (≤5years,5-10years,>10years) the frequency of the order of16cases,21cases,61cases, but can not prove that there are differences between the various syndromes (P in terms of duration of diabetes>0.05), but Phlegm blood stasis blocking collaterals group with increasing duration of diabetes, the proportion gradually increased in> the course of10years accounted for75%(21/28).7.Press the lower extremity arterial intima-media thickened or not the group (A group of lower extremity arterial intima-media thickened, group B is no lower extremity arterial intima-media thickened group):7.1There was no significant difference (P>0.05) in the smoking history.7.2There are significant differences in the two groups (p<0.05) in age.7.3There are significant differences in the two groups (p<0.05) in the ABI.7.4There was no significant difference (P>0.05) in the BMI.7.5There was no significant difference (P>0.05) in diabetes and duration, were significantly different (p<0.05) in HbA1c.7.6The two groups in hypertension, dyslipidemia no significant difference (P>0.05).7.7There are significant differences between the two groups (P in terms of coronary heart disease<0.05), no significant difference (P in terms of merger and cerebrovascular diseases>0.05).7.8The two groups in fatty liver and lipid levels (TG, LDL-C, HDL-C) were not significantly different terms.7.9There was no significant difference (P>0.05) in UA levels.7.10No significant difference (P>0.05)6.10groups in carotid intima-media thickened or not respect.7.11between the four groups conducted every two syndromes fourfold table X2test, Fisher’s exact test can not be considered of lower extremity arterial intima-media thickened of a difference between the groups.Conclusion1The proportion of Phlegm blood stasis blocking collaterals group gradually increases with the duration of diabetes increasing.The group is accounted for75%(21/28) in the course of more than10years,which is the highest group combined coronary heart disease and cerebrovascular disease.2In terms of HbA1c, compared with Both Qi and Yin deficiency, Yin deficiency and dryness-heat group and Phlegm wet resistance group were significantly different from it.In terms of BMI, compared with Both Qi and Yin deficiency,there are significant differences between phlegm wet resistance and Phlegm blood stasis blocking collaterals, so blood glucose levels and BMI might be the reference of MS TCM type.3To ABI value of0.9for the sector, the lower extremity arterial intima-media thickened is great significance in the determination of lower extremity arterial disease.4Long-term high blood sugar levels can increase the risk of lower extremity arterial intima-media thickened, which in turn also indicates that there are serious anomalies in patients with glucose metabolism.5The lower extremity arterial intima-media thickened has important significance in the terms of coronary heart disease. |
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