The Technical Study Of Thiacloprid And Bupirimate And The Synthesis And Activity Of Neonictinoid Insectides Thiazoles Ramification Compound

There were three research contents in this paper. Firstly, the study about the synthesis and activity of the neonicotinoid insecticides ramification compounds. Secondly, the study of technology of thiacloprid; Finally, the study about technology of bupirimate.The neonicotinoid thiazole ramification insecticide was succeed developed by Bayer company in Germany firstly, which became a milestone and was a reformation in the research filed of pesticide, and also be used as the synthesis template of new type insecticide. In this paper, the neonicotinoid insecticides ramification compound have been synthesized successfully through similar synthesis and followed the creation principle of new pesticide, after refer to a mount of literature and under the basis have been investigated. The structure of the compound was examined by gas chromatograph-mass spectrometer (GC-MS) and nuclear magnetic resonance spectrometer (NMR), respectively. Meanwhile, partly compound have been shown well results in the test of the biological activity. Its structure was given below:Thiacloprid is safety to human and animals and it’s smell is gentle. Effective components of the vapor pressure is not high, so it don’t pollute the air and it’s also has low toxicity, no effect on marine life basically. Therefore, the synthesis process of thiacloprid have become one of research hotspots in the pesticide field today. In this paper, the process was improved, sodium carbonate as acid-binding agent, ethyl acetate and DMSO as mixed solvent. Compared with previous reports, this synthetic process reduced pigment, simple process and shorten the reaction time. Those conditions are the optimum process conditions of the present study.Bupirimate has high efficient broad-spectrum resistance, strong suction within the conductivity and resistance to rainwash. Moreover, it has excellent properties for long-lasting effect, low toxicity as well as excellent environment compatibility after drug delivery. In this paper, after one-step method by ethellorimol and N,N-dimethyl sulfonyl chloride, sodium carbonate as acid-binding agent and refluxed with methylbenzene as solvent therein, bupirimate were obtained after dehydration. Compared with the previous literature, the advantages is the reduction of the types of materials and dosage, although the reaction time was shortened, the production rate was as high as 95%, purity reached 98.6% simultaneously. Additionally, we attained favourable industrial benefit by industrial production.