Study On Synthesis,structure And Properties Of Benzimidazole Ligand Containing Sulphur And Complexes

In recent years, the design and synthesis of dimethyl dithiocarbamate has attracted more and more concern. In coordination complexes, this kind of ligands because of the sulfur atom as a ligand has shown a rich diversity whether in the way of bond or in the molecular structure, and the ligands have been widely used in many fields, such as rubber processing, lubricant additives, bio-medicine and waste water treatment. Therefore, to research the relevant structure and property of the series of metal complexes containing sulfur ligands and coordination complexes can not only enrich the theory of bond, but also has potential values of applications in the fields, such as the environment, medicine and materials science.In this paper, N, N- bis(2- Benzimidazolylmethyl) dithiocarbamate(K0) are synthesized with the excellent properties of dithiocarbamates and benzimidazole combined. Then the previous synthesis is used as ligand and a new series of binary and ternary metal complexes are synthesized. The structures are as follows: [Cu(K0)2](H2O)(1), [Zn(K0)](NO3)(2), [Co(K0)2](H2O)(3), [Ni(K0)2](H2O)(4),[Mn(K0)](NO3)(5),[Cd(K0)](NO3)(6),[ Ag2(K0)](NO3)(7), [Zn(K0)2Py](CH3OH)(8),[Ag(K0)(Phen)2](NO3)(9). Characterization results show that the spatial geometry of the ligand is four-coordinate tetrahedral structure. In complexes from 1 to 9, complexes 3 and 4 may be four-coordinated square planar structure. Complexes 2, 5 and 6 are likely to be four-coordinate tetrahedral structure. Complex 8 is five-coordinated trigonal bipyramidal structure. And complex 9 is six-coordinated octahedral structure.In terms of biological properties, this paper focuses on the exploration of the mechanism of action between the ligand and complexes with DNA as well as the research of antioxidant activity. Experimental results show that the ligand and complexes may be combined with DNA in form of intercalation mode. Compared with the ligand, complexes have stronger binding ability. In the study of antioxidant activity, the main measurement of scavenging rate is conducted in the two types of free radical, hydroxyl(OH ?) ions and superoxide anion(O2- ?). The results show that the antioxidant activity ability of dithiocarbamate antioxidant complex is prominent. These research results have a certain reference value for further understanding of the potential properties of dithiocarbamate complexes.