Preparation Of PtPd Nano-particles And Its Application For Glucose Sensors

With another endless variety of new materials and the development of electrochemical glucose sensor in terms of applications, the development of non-enzymatic electrochemical glucose sensor focus on glucose electrochemical sensor research. Not only can detect glucose in blood sugar levels, but also for the qualitative detection of glucose content of food substances are also important. In this paper, the petal-like PtPd alloy nanoparticles,network-like PtPd alloy nanoparticles and stone-like Au@PtPd alloy nanoparticles were prepared and were constructed sensor electrode for glucose. The size, morphology,composition and catalytic activity for glucose oxidation of prepared nanoparticles were investigated.I In this study, the PtPd alloy nanoparticles were synthesized by reverse microemulsion method at room temperature. The structure, size and composition of PtPd nanoparticles were characterized by using X-ray diffraction（XRD）, high-resolution transmission electron microscopy（HRTEM） and X-ray energy dispersive spectroscopy（EDS）. A novel non-enzymatic electrochemical sensor for detecting glucose was developed with fixing the PtPd nanoparticles on the glassy carbon electrode surface（PtPd/GCE）. The XRD result indicated that PtPd nanoparticles are unordered alloy with face central cubic（fcc） structure. The HRTEM imagies showed that the PtPd alloy nanoparticles are aggregated with high density of surface defects, such as twin boundaries, dislocations and stacking faults. The evaluation of sensor performance demonstrated that PtPd/GCE exhibits high sensitivity, wide linear relationship and specificity for glucose. The better linear relationship between current and concentration was showed in the range of glucfose concentration of 1×10-4 M to 4×10-2 M. The low detection limit of glucose was 2.45 μM.Moreover, the sensor was exhibited good stability, reproducibility, and perfect anti-interference performance toward ascorbic acid（AA）, uric acid（UA）, and fructose（Fru）.In conclusion, the developed electrochemical sensor can supply a feasible tool for deterning glucose.II In this chapter, the network-like PtPd alloy nanoparticles were prepared through reduction of potassium borohydride（KBH4） in N,N-dimethylformamide at room temperature. The PtPd/GCE sensor for detecting glucose was built. The performance of sensor were characterized by cyclic voltammetry（CV） and time-current curve（i-t）.Experimental results show that: the developed sensor showed a wide linear range of 1×10-4M to 8×10-2 M with a low detection limit of 0.32 μM for glucose.III The stone-like Au@Pt2Pd1 core-shell nanoparticles were prepared through two steps reduction in one pot at room temperature. The structure, morphology and compositionwere characterized by XRD, HRTEM and EDS. Experimental results show that: the developed sensor showed a wide linear range of 5×10-4 M to 8×10-2 M with a low detection limit of 0.33 μM for glucose.IV Based on the above experiments, in order to further investigate the effect of transition metals on the Pt based catalyst, Pt₃Ru₁ alloy nanoparticles were synthesized by reverse microemulsion method at room temperature. The evaluation of sensor performance demonstrated that Pt₃Ru₁/GCE exhibit excellent high sensitivity, specificity and linear relationship in most wide renge of concentration of glucose. The better linear relationship between current and concentration was showed in the range of glucfose concentration of5×10-7 M to 10-2 M. The low detection limit of glucose was 0.30 μM.