The Degradation Of Streptomycin In Water Evironment

Animal husbandry is a pillar industry in the Inner Mongolia region, and the veterinary antibiotics were used widely. A large number of antibiotics damage to the environment, in recent years, the pollution of antibiotics was widely attention, so the study about the environmental behaviourof antibiotics is necessary. This paper mainly studies the degradation behavior of Streptomycin in water environment.First, the environmental factors including-pH, temperature, light, concentration, coexisting substanceswere studied in distilled water system.The degradation of Streptomycinwas acceleratedin acidic and alkaline conditions. The higher temperature may accelerate the degradation of Streptomycin, the degradation rates increased 2.48 fold for a 10℃ increase in temperature. Anionic surfactant, calcium ion and the presence of humic acid accelerated the degradation of Streptomycin, however, cationic surfactant, copper ion and cadmium ion inhibits the degradation of Streptomycin.Second, in different aquatic environments, the microorganism was the main consideration factor, the sequenceofdegradation of Streptomycinwas cattle wastewater> lake water> tap water. In sediment for influence factors, we considered the effect of microorganism and the effect of different saturated water content, the results found that the higher the saturation water content can speed up the degradation of Streptomycin.Third, the main degradation intermediates/products were identified by liquid chromatography-mass spectrometry (LC-MS), and an alternative degradation pathway was proposed. The final degradation products were streptose, streptidine and N-methyl-L-glucosamine under the condition of acidic and neutral, however, the rearrangement reaction make streptose to the maltolunder the condition of alkaline. The antibacterial property of Streptomycin and degradation intermediates wae studied, and escherichia coli and staphylococcus aureus was the target bacteria antibacterial property, and results showed that the parent compound was more toxic than the transformtion products.