The Effect Of CpG On Growth Performance,Physical And Chemicai Indicatators And Immunuzationg Of Sows And Weaned Piglets

The paper studied the effect of CpG on growth performance, physical and chemical indicators and immunization of sows and weaned piglets by adding certain amounts of CpG product (sows:0.5% and 0.7%; weaned piglets:1% and 1.5%) into pig basic diets. The impacts on pig farm production benefits were also evaluation.The results showed:1. Compared with the control group, change of total litter size, alive litter size, litter size at weaning, weaning weight or weaned piglet survival rate was non significant (P>0.05). However, significantly positive impacts on feed intakes of sows were observed, as well as the piglet’s weight gain (P<0.05). Non of weaned piglet illness (cough, asthma, diarrhea, weakness or death) occurred by CpG addition in basic diets(P>0.05), neither the feed conversion ratio (FCR, P>0.05). While the feed intakes and the body weight gains of weaned piglets shown significantly increased (P<0.05).2. There was no significant effect on sows’ liver and kidney functions by adding CpG product into the diets (P>0.05), whereas a certain protective effect occurred in CpG feeding group, compared with the control group (P>0.05).3. The Classical swine fever virus (CSFV) titer in sows and Porcine circovirus (PCV) titer in weaned piglets were compared between CpG feeding group and control group. The decreasing speed of CSFV-antibody level in sows was slightly delayed by feeding CpG product, and the antibody positive rate was maintaining in a high level(P<0.05). The serum antibody against PCV in piglets was also decreased in a certain extent, while the antibody positive rate was increased (P<0.05).4. The serum IgA level was measured by ELISA. No effect to IgA was measured in CpG feeding sows rather than control (P>0.05). An increase of IgA was observed in CpG feeding piglets (P<0.05).Thus, we concluded the production performance and immunization of both sows and weaned piglets can be enhanced by adding certain amounts of CpG product into the basic pig diets without impacting their liver and kidney functions.