Echocardiogram Evaluation Of The LVEFfects Of Emergency PCI On Ventricular Diastolic Function Of The Patients With Acute STEMIf Trends Of Left Ventricular Diastolic Function Changes In Two Months After Emergency PCI On Patients With Acute STEMI

Objective The objective of this study is to investigate the short-term LVEFfects of emergency percutaneous coronary intervention (PCI) surgery on the diastolic function of left ventricular in patients with acute ST segment elevation myocardial infarction (STEMI). The study consists of two components.1). Using echocardiogram, we evaluate, at different time points in a two-month stint, the change trends of left ventricular diastolic function indexes in STEMI patients who have undergone emergency PCI.2). In the study, correlations between the E/E’ ratio by echocardiogram and the left ventricular end diastolic pressure by cardiac catheter measurements are sought.Method1). Echocardiogram examinations were conducted on39cases of STEMI patients at elaborately designed times, i.e., prior to, immediately after, two weeks and two months after the PCI surgery, respectively. Measured parameters: diastolic mitral inflow velocity E peak, A peak and E/A ratio; early diastole velocity E’ at four mitral valve annulus sites, and extracted E/E’ ratio; corresponding late diastolic velocity A’ and extracted E’/A’ ratio; blood deceleration time (DT) at early diastolic mitral; pulmonary vein isolation (PVI); left atrial volume index (LAVI); front/rear diameters, and LVEF value of the left ventricle; early diastole velocity E’ at four mitral valve annulus sites, and extracted E/e ratio.2). A6F pigtail catheter, with a pressure transducer connected to the other end, was inserted into the left ventricle through either right radial or femoral artery, to record the left ventricular end diastolic pressure (LVEDP).Results Compared correspondingly with to what were measured prior to the emergency PCI,1) the E’ values at posterior wall decreased with P <0.05, respectively; 2). Compared with the values prior to and immediately after the surgery, The left atrial volume index (LAVI) increased significantly in two weeks and two months after PCI respectively, with a P <0.05;3). No significant changes trends of E’velocities (at the posterior wall) were observed in the four measurements at different time points. Despite of a P>0.05, all E’velocities measured smaller than8cm/s.4). No relations were observed between E/E’ and LVEDP during STEMI.Conclusion1). Left ventricular diastolic dysfunction tends to decrease in the first two weeks among and even two months after the STEMI patients with emergency PCI;2). The left atrial volume index (LAVI) increased significantly in two weeks and two months after PCI;3).There are no apparent correlations between LVEDP and E/E’ prior to and immediately after emergency PCI.