Changes And Significance In Expression Of Plasma Hydrogen Sulfide In Patients With Acute High Altitude Pulmonary Edema

Objective： To explore the expression and significance of plasma endogenoushydrogen sulfide （H₂S） in patients with acute high altitude pulmonary edema.Method： Determination of plasma H₂S content through the use of sensitive sulfurelectrode method （PXS-270type, Leici）. There were38cases of acute high altitudepulmonary edema （case group） and35healthy subjects （control group） into the Yushuarea （3600m above sea level）.Parallel statistical analysis of the data finishing.Statistical methods: SPSS17.0statistical software for data analysis, the healthysubjects and the patients before and after treatment of plasma H₂S all were shown asmeans士standard deviation （x士s），Between the two groups were compared usinganalysis of variance. The inspection standard was alpha=0.05.Results：1.The results showed there were statistically significant difference of H₂Slevel concentration before and after the treatment of patients with acute high altitudepulmonary edema was （t=8.219，P <0.01），and the patients before treatment with H₂Sconcentration level was slightly lower than the patients after treatment.2.There werestatistically significant difference of H₂S level concentration with the healthy controlgroup and case group with acute high altitude pulmonary edema （F=188.951，P <0.01）， and the patients before and after treatment with plasma H₂S concentrationlevels lower than the healthy control group.Conclusions：1.Acute high altitude pulmonary edema plasma H₂S concentrationlower than the healthy control group.2. Acute high altitude pulmonary edema patientsbefore treatment after treatment plasma H₂S concentrations below.