| Objective:Cerebral infarction is a common refractory disease hazardous to human health and life safety. After cerebral infarction, it will cause encephaledema and disorder in cerebral blood flow, tissue metabolism and other aspects. The morphological changes of cerebral infarction can be reflected by modern imaging technology; however, the pathological disorder cannot be evaluated. The extent of damage of cerebral cortex and its connected fiber in lesion area could be reflected sensitively by electroneurophysiological examination. The state of brain dysfunction with cerebral infarction could also be reflected. This article discusses the characteristics of changes of SEP, MEP, threshold and SP, and their relationship with the severity of the disease of patients with cerebral infarction.Method:50patients with the unilateral hemisphere cerebral infarction were chosen as the patient group. The unilateral and the contralateral side were examined respectively.50healthy people were chosen as the control group. Myodynamia was in0-Ⅳ level. Peripheral and other central nervous lesions were eliminated and confirmed by MRI scans. Patients agreed and cooperated with tests actively. Examination on MEP, SEP and SP were taken for patients in both the patient group and the control group. SEP central conduction time (CCT), MEP central motor conduction time (CMCT), the threshold and the changes of SP were observed. The central sensory of unilateral side, the motor conduction time and threshold and the characteristics of changes of cortex magnetic stimulation resting period were analyzed in the patient group.Result:1. Result of SEP:38cases in50patients were found abnormal of the patients group, accounting for76%. The CCT of SEP in the unilateral side of the upper and lower limbs was extended compared with that of the contralateral side and the control group’s. The difference was statistically significant (P<0.01).2. Result of MEP:45cases were found abnormal in MEP in the unilateral side of the patient group, accounting for95%.The CMCT in the unilateral side of the upper and lower limbs was extended compared with that of the contralateral side and the control group’s. The difference was statistically significant (P<0.01).3. Result of SP and threshold of motor cortex:The results of SP in22cases were significantly extended than the control group’s. The difference was statistically significant (P<0.01). The threshold was significantly higher than the control group’s. The difference was statistically significant (P<0.01).4. The total number of abnormality in SEP, MEP, threshold and SP examination of50patients with cerebral infarction was45cases (90%).Conclusion:1. SEP reflected functional status of specific somatic sensory pathway, brainstem reticular structure and cerebral cortex at some extent. It would evaluate the functional status of cerebral corte, somatosensory cortex and somatosensory cortex pathway. It also involved in the judgment of the prognosis of cerebral infarction.2. Examination of MEP could obtain objective evidences of the severity of pyramidal tract injury. MEP could not only evaluate the severity of patient’s neurological function, but also provide an objective assessment of prognosis.3. MEP motor threshold and SP could reflect excitability of cerebral cortex objectively and quantitatively. It played a supplementary role in the clinical judgment of prognosis.4. The abnormal rate of SEP, MEP and threshold and SP examination of patients with cerebral infarction was90%. Cerebral sensory, motility and cortex excitability could be fully reflected by those three factors. It provided evidences for clinical diagnosis, treatment and prognosis.5. Electroneurophysiology examination was non-invasive, simple and cheap. It could be used to detect abnormalities faster than imaging method as well as to observe the objective disease indicators dynamically and to play essential role in the prognosis of patients. |
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