The Clinical Value Of Transcranial Magnetic Stimulation Evoked Potential,Resting Stage And Somatosensory Evoked Potential In The Acute Stage Of Cerebral Infarction

Objective: Cerebral infarction(CI),also as Ischemic stroke,is one of the neurological impairment clinical syndrome because of Ischemic and anaerobic necrosis of local brain tissue caused by various factors.CI is a common refractory diseases which had a high rate of morbidity,disability and death and a grave harm to human health and life safety.So,early correct evaluation of craniocerebral function had a important role in guiding medical decisions,reasonably allocating medical resources and selecting treatment options.Nerve electrophysiological examination(SEP?MEP?SP)can sensitively respond the injury degree of cerebral cortex and neural connection fiber in lesion area and the brain dysfunction of CI.In this study,we investigate the clinical significance of nerve electrophysiological examination on acute phase and prognosis of patients with CI via investigating the estimated value of SEP,MEP and SP on patients with acute cerebral infarction merged with a limb movement dysfunction Methods: 139 cases of patients with CI(age: 31-79,average age 59.49±12.95)were selected from March 2015 to October 2016 from neurology department in Lake Hospital.All patients were first diagnosed as acute cerebral infarction merged with a limb movement dysfunction,and the infarct is located on one side of the brain verified by head nuclear magnetic resonance.The NIHSS,BI,myodynamia and MRC were measured.All patients were divided into two groups according to myodynamia.The SEP,MEP and SP were measured in both uninjured and affected side admission within one week,and Rankin were measured in all patients after 3 months.Results: There was a significant difference of SEP,MEP and SP between two groups(P<0.01).The composition of electrophysiologic examination had a significant difference between two groups acording to clinical scale score(P<0.01).There was a relationship between electrophysiological test results and prognosis of patient.All patients had the same therapeutic method.The favourable prognosis cases was 11 cases in 28 cases who had a deficiency SEP,37 cases in 60 cases who had a prolong SEP and 33 cases in 51 cases who had a normal SEP,and there was a significant difference of therapeutic effect according to SEP results among three groups(P<0.05).The favourable prognosis cases was 12 cases in 46 cases who had a deficiency MEP,54 cases in 77 cases who had a prolong MEP and16 cases in 16 cases who had a normal MEP,there was a significant difference of therapeutic effect according to MEP results among three groups(P<0.05).The favourable prognosis cases was 12 cases in 46 cases who had a deficiency SP,62 cases in 86 cases who had a prolong SP and 7 cases in 7 cases who had a normal SP,there was a significant difference of therapeutic effect according to SP results among three groups(P<0.05).Conclusion: There ia a great value of MEP,SP and sEP in assessment and predict the functional recovery in patients with CI in early stage.