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Clinical Study Of The Relationship Between The Amount Of Urate Crystal Deposition Of Hand-foot And Hand-foot Focusing On

Posted on:2015-10-16Degree:MasterType:Thesis
Country:ChinaCandidate:Y LiuFull Text:PDF
GTID:2284330431480720Subject:Integrative Medicine
Abstract/Summary:PDF Full Text Request
With the performance of the sudden appearance of the limb and joint swelling andsevere pain, Gouty arthritis is a class of metabolic diseases.Present study suggests that thedisease is mainly caused by the purine metabolism, uric acid excessive or excretion of uricacid.With the main reason of Clinical visits is elevated by blood of uric acid level, imagingstudies can be found urate crystals deposite in the joints, surrounding tissue, oftenassociated with hypertension, hyperlipidemia, type2diabetes, obesity,and insulinresistance.The complex etiology of this disease, recurrent, complications, it was called "theking of diseases."Most experts believe that gouty arthritis is often associated with depositionof urate crystals stimulate tissue, causing an inflammatory reaction,considering that there is alink of urate deposition、temperature, and feeding status, etc.Distal limb temperature islower than the center temperature,and blood supply of toes, finger tip is less than theproximal uric acid deposition in parts, easy extremity blood supply is poor, low temperature.Through a lot of clinical observation, it was found that temperature and blood supply theorycannot fully explain the reason of uric acid salt deposition site, considering of uric acidcrystal deposition in the hand and foot except temperature and the blood supply must have aclose relationship with inevitable and siblings,ObjectiveIn dual-source spiral CT limb joints urate crystal deposition as a means of imaging,thetopic observes and analyzes185cases of hand-foot site of gout patients of urate crystaldeposition.Starting from sports medicine, to explore new ideas of the correct, rational,comprehensive treatment for clinical gout,the topic explores the relationship between thedistribution of Hand and foot urate crystal deposition sites and hand-foot focusing on.MethodsThis study selected185cases of gouty arthritis diagnostic criteria of patients, including101cases of male, female84cases, age13~91years, mean age52.41±16.18years old;blood uric acid (166~806) μ mol/L, average (343.34±109.28) μ mol/L, duration of1days to27.75years, the average duration of28.84months to55.4months. All patients weretreated from2012July to2013April. Patients signed the informed consent, detailed recordsof patient’s name, sex, age, clinical symptoms, blood uric acid and parallel dual source CTuric acid crystal imaging examination, observe and record the number of uric acid crystaldeposition location and deposition, the data was collected for statistical processing.Results185cases of gout patients,184cases found urate crystal deposition of urate crystalsstatistics hands full deposit240sites.Hand and foot urate deposition site rule as follows:metacarpophalangeal joints, metatarsophalangeal joint, toe toe joint, wrist tarsal joints, ankle,finger joints.(1) the uric acid crystal deposit in the palm of your hand and foot main side, inthe back of the hand and foot back occasionally;(2) the palm: metacarpophalangeal joint1273position,347finger joint, wrist joint parts of26parts, including2~4metacarpophalangeal uric acid crystal deposition rare joint and wrist around the tendon andligament;(3): ankle plantar metatarsophalangeal joint890position, toe joint366parts,316parts, a total of179tarsal joint parts, especially in the first toe joints and the tarsal joint ofheel, ankle joint tissue deposition of uric acid crystals as much.ConclusionsUric acid crystals in the foot in patients with gout parts are deposition, deposition sitesexcept the extra articular, articular tissues are also a large number of uric acid crystaldeposition. Uric acid deposition site has the relationship with the main focus on the positionof anatomical motion structure, locating in the dorsal and volar tendon.
Keywords/Search Tags:Serum uric acid, gout, uric acid crystal, limbs, focus
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